Therapeutic Potential for Inhibition of HIV Activation

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Belzil, Camille
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Lethbridge Undergraduate Research Journal
The Human Immunodeficiency Virus (HIV) is as simple as it is successful. Consisting of only relatively few elementary molecules, it is exceedingly hard to detect and has proven both difficult and expensive to treat. Treatment modalities are limited by the simplicity of its life cycle and the already compromised immune systems of patients. Current antiretroviral treatments are reasonably effective, but far too expensive for widespread distribution. Similarly, education can only go so far in combating such a virulent disease that is infectious in the absence of symptoms. This scenario presents an epidemiological dilemma: The highest rates of HIV prevalence are in underdeveloped and uneducated parts of the world. The areas worst afflicted lack the finances and infrastructure to initiate effective treatment programs. This paper discusses the pathway for activation of the HIV provirus, and proposes the use of inexpensive plant extracts to slow rates of transmission and the progression from HIV infection to AIDS. It also addresses the growing problem of HIV/tuberculosis co-infection and use of combined treatments to slow infection rates of both diseases.
HIV Infections -- Treatment , HIV Infections