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dc.contributor.supervisor Schultz, Elizabeth
dc.contributor.author Pageni, Utsab
dc.contributor.author University of Lethbridge. Faculty of Arts and Science
dc.date.accessioned 2021-10-18T20:03:01Z
dc.date.available 2021-10-18T20:03:01Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/10133/6064
dc.description.abstract Cellular polarity is a fundamental aspect of all multicellular organisms that enables certain cell types to carry out their functions. Therefore, cell polarity formation is an important basis for understanding the molecular linkage between morphology and cellular functions. In Arabidopsis, the position of root hairs is mediated by intercellular flow of the phytohormone auxin, for which directional signaling is determined by the polar subcellular localization of PIN-FORMED (PIN) transport proteins. My research primarily focuses on establishing plant lines that will later allow correlation of changes in proteins distribution with changes in cell polarity and plant morphology. Mutations in genes such as FORKED1, SCARFACE, PINOID and RON3 result in defective localization of PIN proteins in various tissues, by affecting PIN phosphorylation status (PID and RON3) or endomembrane dynamics (FORKED1 and SCARFACE). This study will introduce fluorophore labeled fusion proteins into FORKED1, SCARFACE, PINOID and RON3 mutants. en_US
dc.language.iso en_US en_US
dc.publisher Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences en_US
dc.relation.ispartofseries Thesis (University of Lethbridge. Faculty of Arts and Science) en_US
dc.subject auxin en_US
dc.subject PIN en_US
dc.subject cell polarity en_US
dc.subject protein localization en_US
dc.subject Auxin -- Research en_US
dc.subject Auxin -- Molecular aspects -- Research en_US
dc.subject Polarity (Biology) -- Research en_US
dc.subject Root hairs en_US
dc.subject Plant regulators -- Research en_US
dc.subject Arabidopsis -- Roots -- Development -- Research en_US
dc.subject Arabidopsis -- Roots -- Formation -- Research en_US
dc.subject Arabidopsis -- Roots -- Morphology -- Research en_US
dc.subject Roots (Botany) -- Morphology -- Research en_US
dc.subject Dissertations, Academic en_US
dc.subject Carrier proteins en_US
dc.title Generating plant lines with markers designed to assess cell polarity defects at the molecular level en_US
dc.type Thesis en_US
dc.publisher.faculty Arts and Science en_US
dc.publisher.department Department of Biological Sciences en_US
dc.degree.level Masters en_US
dc.proquest.subject 0379 en_US
dc.proquest.subject 0307 en_US
dc.proquestyes Yes en_US


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