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dc.contributor.supervisor Gibb, Robbin L.
dc.contributor.author Jenkins, Serena
dc.contributor.author University of Lethbridge. Faculty of Arts and Science
dc.date.accessioned 2021-09-23T15:46:44Z
dc.date.available 2021-09-23T15:46:44Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/10133/6038
dc.description.abstract This thesis explores the impacts of maternal preconception experience on the development of brain and behavior in the next generation. Chapter 1 provides a review of the literature on prenatal and preconception exposure to common recreational drugs of abuse, nicotine and alcohol. The review covers behavioral, neuroanatomical, molecular/epigenetic, and physiological impacts of developmental drug exposure. Chapter 2 discusses the results of an experiment that investigated the early impacts of maternal preconception nicotine and environmental enrichment. Chapter 3 covers how maternal preconception nicotine and enrichment continue to affect development in adolescent and adult offspring. Chapter 4 discusses an experiment into the impacts of maternal preconception alcoholism on offspring development throughout life. Chapter 5 presents a brief general conclusion. The overall goal of this thesis is to highlight how maternal experiences prior to conception can have just as significant an impact on offspring development as much more thoroughly studied prenatal experiences. en_US
dc.language.iso en_US en_US
dc.publisher Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience en_US
dc.relation.ispartofseries Thesis (University of Lethbridge. Faculty of Arts and Science) en_US
dc.subject Behavioral Neuroscience en_US
dc.subject Alcohol en_US
dc.subject Alcohol -- Physiological effect en_US
dc.subject Animals -- Drug use en_US
dc.subject Dissertations, Academic en_US
dc.subject Nicotine en_US
dc.subject Nicotine -- Physiological effect en_US
dc.subject Preconception care en_US
dc.title Consequences of maternal preconception nicotine and alcohol: a rodent model of the long-term effects on offspring brain and behavior en_US
dc.type Thesis en_US
dc.publisher.faculty Arts and Science en_US
dc.publisher.department Department of Neuroscience en_US
dc.degree.level Ph.D en_US
dc.proquest.subject 0602 en_US
dc.proquest.subject Neurosciences [0317] en_US
dc.proquest.subject Behavioral sciences [0602] en_US
dc.proquest.subject Animal sciences [0475] en_US
dc.proquestyes Yes en_US


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