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dc.contributor.supervisor Sutherland, Robert J.
dc.contributor.supervisor McDonald, Robert J.
dc.contributor.author Lee, Justin Quinn
dc.contributor.author University of Lethbridge. Faculty of Arts and Science
dc.date.accessioned 2019-06-19T15:17:36Z
dc.date.available 2019-06-19T15:17:36Z
dc.date.issued 2019
dc.identifier.uri https://hdl.handle.net/10133/5402
dc.description.abstract Contemporary views on the organization of long-term memory (LTM) suggest the hippocampus is involved in a unique category of LTM. Recent experiments illustrate that hippocampal damage before and after a learning episode result in different patterns of amnesia, and many types of memory are affected by damage after the learning episode. These results challenge contemporary views of LTM organization, and motivate the present thesis. We describe a concept, termed heterarchic reinstatement (HR) to account for the pattern of amnesia following hippocampal damage. We observed a pattern of results, in both hippocampal activity and amnesia following damage that support the HR view. However, an experiment using temporary inactivation reveals limitations of the HR view. Thus, we provide a new predictive model of hippocampus and memory, termed the Memory Manifold Theory (MMT), that incorporates the HR concept and our observations along with the broader research literature. en_US
dc.description.sponsorship NSERC en_US
dc.language.iso en_US en_US
dc.publisher Lethbridge, Alta.: Univeristy of Lethbridge Dept. of Neuroscience en_US
dc.relation.ispartofseries Thesis (University of Lethbridge. Faculty of Arts and Science)
dc.subject Hippocampus en_US
dc.subject Rat en_US
dc.subject Memory en_US
dc.title Patterns of hippocampal amnesia and population activity in rats: Implications for categorical and single-process models of long-term memory organization en_US
dc.type Thesis en_US
dc.publisher.faculty Arts and Science en_US
dc.publisher.department Department of Neuroscience en_US
dc.degree.level Ph.D en_US
dc.proquest.subject Neurosciences [0317] en_US
dc.proquest.subject Behavioral psychology [0384] en_US
dc.proquestyes Yes en_US
dc.embargo No en_US


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