The effect of playful experiences on the plasticity and metaplasticity of the brain

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dc.contributor.authorHimmler, Brett T.
dc.contributor.authorUniversity of Lethbridge. Faculty of Arts and Science
dc.contributor.supervisorPellis, Sergio M.
dc.contributor.supervisorKolb, Bryan
dc.date.accessioned2012-06-04T18:30:44Z
dc.date.available2012-06-04T18:30:44Z
dc.date.issued2011
dc.degree.levelMasters
dc.descriptionix, 67 leaves ; 29 cmen_US
dc.description.abstractThe influence of play behavior on the brain was investigated through plasticity and metaplasticity methodology. Regions in both cortical and sub-cortical areas were investigated. Animals in both studies either experienced play with juvenile partners or did not experience play by being paired with an adult. Play experience alone was shown to affect the plasticity in the prefrontal cortex, although it did not show structural changes to sub-cortical regions. If animals were given nicotine after play experiences, the affects of play in the prefrontal cortex were abolished. In addition, playful behaviors appear to prime some sub-cortical regions of the brain for expression of later plasticity. Thus, play appears to alter the structure of multiple brain areas, but do so in different ways.en_US
dc.identifier.urihttps://hdl.handle.net/10133/3081
dc.language.isoen_USen_US
dc.publisherLethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, 2011en_US
dc.publisher.departmentDepartment of Neuroscienceen_US
dc.publisher.facultyArts and Scienceen_US
dc.relation.ispartofseriesThesis (University of Lethbridge. Faculty of Arts and Science)en_US
dc.subjectNeuroplasticityen_US
dc.subjectNeuroplasticity -- Researchen_US
dc.subjectNeuroplasticity -- Animal modelsen_US
dc.subjectRats as laboratory animalsen_US
dc.subjectRats -- Behavioren_US
dc.subjectPlay behavior in animalsen_US
dc.subjectPlay behavior in animals -- Researchen_US
dc.subjectDissertations, Academicen_US
dc.titleThe effect of playful experiences on the plasticity and metaplasticity of the brainen_US
dc.typeThesisen_US
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