Alkylamido lutetium complexes as prospective lutetium imido precursors: synthesis, characterization and ligand design
Loading...
Date
2025
Authors
Knott, Jackson P.
Hsiang, Shou-Jen
Hayes, Paul G.
Journal Title
Journal ISSN
Volume Title
Publisher
Royal Society of Chemistry
Abstract
Mixed alkylamido lutetium complexes, LiPrLu(CH2SiMe3)(NHCPh3) (7CPh3) and LiPrLu(CH2SiMe3)(NHDipp) (7Dipp) (LiPr = 2,5-[iPr2P = N(4-iPrC6H4)]2C4H2N−), were synthesized by addition of a bulky primary amine, NH2R (R = CPh3, Dipp) (Dipp = 2,6-iPr2C6H3) to the dialkyl complex LiPrLu(CH2SiMe3)2 (6). Unlike complexes supported by the related pincer ligand LPh (LPh = 2,5-[Ph2P = N(4-iPrC6H4)]2C4H2N−) these species proved resistant to C–H cyclometalative processes. Attempts to access lutetium imdes via addition of 4-dimethylaminopyridine (DMAP) to 7CPh3 and 7Dipp promoted disproportionation, affording 0.5 equivalents of the corresponding bisamide complexes LiPrLu(NHCPh3)2 (8CPh3) and LiPrLu(NHDipp)2 (8Dipp), respectively, as well as 0.5 equivalents of LiPrLu(CH2SiMe3)2, which decomposed in the presence of DMAP. Incorporation of internal Lewis bases was accomplished by replacing the N-aryl substituents in LiPr with 4,6-dimethylpyrimidine groups (LPm, 11). The correspondng dialkyl lutetium complex LPmLu(CH2SiMe3)2 (12) was prepared, from which loss of SiMe4 occured over a period of hours in benzene-d6 solution.
Description
Open access article. Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC 3.0) applies
Keywords
Citation
Knott, J. P., Hsiang, S.-J., & Hayes, P. G. (2025). Alkylamido lutetium complexes as prospective lutetium imido precursors: Synthesis, characterization and ligand design. Dalton Transactions, 54, 6261-6273. https://doi.org/10.1039/D5DT00338E