The role of epigenetics in the maintenance of plant genome stability

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dc.contributor.authorBilichak, Andriy
dc.contributor.supervisorKovalchuk, Igor
dc.date.accessioned2014-06-06T17:55:51Z
dc.date.available2014-06-06T17:55:51Z
dc.date.issued2013
dc.degree.levelPh.Den_US
dc.degree.levelPhD
dc.descriptionxv, 280 leaves : ill. ; 29 cmen_US
dc.description.abstractSignificant alterations in the environmental conditions can have pronounced effects on plant genome stability. Recent evidence argues for a global involvement of the components of epigenetic modules in the regulation of genome homeostasis both immediately after stress exposure and long after environmental cues were acquired. The last observation is of particular interest as the memory of imposing stress can be maintained at the molecular level throughout plant ontogenesis and may be faithfully propagated into the following generation. Our study provides evidence that epigenetic repercussions exerted by stress exposure of parental plants manifest themselves in untreated progeny at all three levels of the epigenetic module: DNA methylation, histone posttranslational modifications and small RNA metabolism. Additionally, the results of our study shed new light on the engagement of the epigenetic machinery in the maintenance of plant genome integrity by counteracting the activity of invading nucleic acids.en_US
dc.identifier.urihttps://hdl.handle.net/10133/3448
dc.language.isoen_CAen_US
dc.proquestyesNoen_US
dc.publisherLethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciencesen_US
dc.publisher.departmentDepartment of Biological Sciencesen_US
dc.publisher.facultyArts and Scienceen_US
dc.relation.ispartofseriesThesis (University of Lethbridge. Faculty of Arts and Science)en_US
dc.subjectEpigeneticsen_US
dc.subjectPlant genomes -- Researchen_US
dc.subjectPlants -- Effect of stress on -- Genetic aspectsen_US
dc.subjectPlants -- Effect of stress on -- Researchen_US
dc.subjectArabidopsis thaliana -- Effect of stress on -- Genetic aspectsen_US
dc.subjectArabidopsis thaliana -- Effect of stress on -- Researchen_US
dc.subjectDissertations, Academicen_US
dc.titleThe role of epigenetics in the maintenance of plant genome stabilityen_US
dc.typeThesisen_US
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