Dietary Ca inhibits waterborne Cd uptake in Cd-exposed rainbow trout, Oncorhynchus mykiss
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Date
2001
Authors
Zohouri, Mohammad Ali
Pyle, Gregory
Wood, Chris M.
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
The effects of chronic exposure to waterborne Cd and elevated dietary Ca, alone and in combination, were examined
in juvenile rainbow trout, Oncorhynchus mykiss. Fish were chronically exposed to 0.05 Žcontrol. or 2.56 g l Cd as
CdŽNO3.2 4H2O and were fed 2% body mass day of control Ž29.6 mg Ca g. or Ca-supplemented trout food Ž52.8 mg
Ca g as CaCl2 2H2O.. Cd accumulated mainly in gill, liver, and kidney. Waterborne Cd inhibited unidirectional Ca
uptake from water into the gill and induced hypocalcemia in the plasma on day 40. Waterborne Cd also induced an
elevated Ca concentration on day 20 in the gill tissue of trout fed the Ca-supplemented diet and a decreased Ca
concentration on day 35 in the gills of trout fed the control diet. Dietary Ca protected against Cd accumulation in gill,
liver, and kidney, but did not protect against the inhibition of Ca uptake into the gill or plasma hypocalcemia. When fed
Ca-supplemented diet and exposed to waterborne Cd, fish showed 35% mortality, compared to 0 2% in control fish and
in the Cd-exposed fish with normal Ca in the diet. Growth, on the other hand, was not affected by any treatment.
Description
Sherpa Romeo green journal
Keywords
Dietary calcium , Gill , Hypocalcemia , Oncorhynchus mykiss , Rainbow trout , Waterborne cadmium
Citation
Zohouri, M.A., G.G. Pyle, and C.M. Wood. 2001. Dietary Ca inhibits waterborne Cd uptake in Cd-exposed rainbow trout,Oncorhynchus mykiss. Comparative Biochemistry and Physiology, Part C, Toxicology and Pharmacology, 130(3): 347-356.