Genomic and epigenomic changes in transgenerational response to cold stress in Arabidopsis thaliana

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dc.contributor.authorRahman, Ashif
dc.contributor.authorUniversity of Lethbridge. Faculty of Arts and Science
dc.contributor.supervisorKovalchuk, Igor
dc.date.accessioned2020-05-07T18:16:07Z
dc.date.available2020-05-07T18:16:07Z
dc.date.issued2020
dc.degree.levelMastersen_US
dc.description.abstractPlants are continuously exposed to various environmental stresses. They employ numerous strategies of resistance and develop a memory of stress exposure for future generations. Abiotic stress, like cold, can prompt the changes in phenotype, genotype, and epigenotype of plants. Plants can establish these as somatic and transgenerational memories. We studied the Arabidopsis thaliana plants exposed to multiple generations of cold stress. We hypothesized that the progeny of plants exposed to 25 generations to cold stress would be genetically and epigenetically more diverse than the parental plants. Our study reveals that multigenerational exposure to cold stress resulted in the physiological changes, as well as changes in the genomic and epigenomic (DNA methylation) patterns across generations. The main changes in the progeny were due to the high frequency of genetic mutations rather than epigenetic changes. Our work supports the existence of transgenerational stress response in plants and demonstrates that genetic changes prevail.en_US
dc.identifier.urihttps://hdl.handle.net/10133/5716
dc.language.isoen_USen_US
dc.proquest.subjectBioinformatics [0715]en_US
dc.proquest.subjectPlant sciences [0479]en_US
dc.proquest.subjectMolecular biology [0307]en_US
dc.proquestyesYesen_US
dc.publisherLethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciencesen_US
dc.publisher.departmentDepartment of Biological Sciencesen_US
dc.publisher.facultyArts and Scienceen_US
dc.relation.ispartofseriesThesis (University of Lethbridge. Faculty of Arts and Science)en_US
dc.subjectArabidopsis thalianaen_US
dc.subjectCold -- Physiological effecten_US
dc.subjectPlant ecological geneticsen_US
dc.subjectPlant geneticsen_US
dc.subjectPlant mutationen_US
dc.titleGenomic and epigenomic changes in transgenerational response to cold stress in Arabidopsis thalianaen_US
dc.typeThesisen_US
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