Characterization of Escherichia coli O157:H7 from super-shedding feedlot cattle

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dc.contributor.authorMunns, Krystyn Danielle
dc.contributor.supervisorSelinger, L. Brent
dc.contributor.supervisorMcAllister, Tim A.
dc.date.accessioned2015-05-05T16:50:40Z
dc.date.available2015-05-05T16:50:40Z
dc.date.issued2015
dc.degree.levelMastersen_US
dc.description.abstractEscherichia coli O157:H7 is a major foodborne human pathogen that causes disease worldwide. Healthy cattle are the primary reservoir of this bacterium and the amount and frequency of E. coli O157:H7 shedding varies among individual cattle. The term “super-shedder” has been applied to cattle that are transiently high shedders (≥104 CFU/g feces). Targeting these cattle for mitigation strategies has been proposed as a means of reducing the incidence and spread of E. coli O157:H7 in the feedlot environment. The objectives of this study were to determine the frequency and duration of the super-shedding state in cattle; and to elucidate phenotypic or genetic differences among E. coli O157:H7 isolates recovered from super-shedding cattle and low-shedder cattle. It was found that the super-shedding state is short lived and lacks continuity and we were unable to successfully identify specific traits among super-shedder isolates that could be used to differentiate them from low-shedder isolates.en_US
dc.embargoNoen_US
dc.identifier.urihttps://hdl.handle.net/10133/3674
dc.language.isoen_CAen_US
dc.proquest.subject0410en_US
dc.proquest.subject0307en_US
dc.proquest.subject0306en_US
dc.proquestyesYesen_US
dc.publisherLethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciencesen_US
dc.publisher.departmentDepartment of Biological Sciencesen_US
dc.publisher.facultyArts and Scienceen_US
dc.relation.ispartofseriesThesis (University of Lethbridge. Faculty of Arts and Science)en_US
dc.subjectEscherichia coli O157:H7en_US
dc.subjectcattleen_US
dc.subjectsuper-sheddingen_US
dc.titleCharacterization of Escherichia coli O157:H7 from super-shedding feedlot cattleen_US
dc.typeThesisen_US
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