Epidemiology and diagnosis of anoplocephala perfoliata in horses from Southern Alberta, Canada

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dc.contributor.authorSkotarek, Sara L.
dc.contributor.authorUniversity of Lethbridge. Faculty of Arts and Science
dc.contributor.supervisorGoater, Cameron P.
dc.contributor.supervisorColwell, Douglas
dc.date.accessioned2008-10-27T17:38:21Z
dc.date.available2008-10-27T17:38:21Z
dc.date.issued2008
dc.degree.levelMasters
dc.descriptionviii, 70 leaves ; 29 cm.en
dc.description.abstractThe cestode Anoplocephala perfoliata is known to cause fatal colic in horses. The epidemiology of the cestode has rarely been evaluated in Canada. I detected A. perfoliata eggs in 4-18% of over 1000 faecal samples collected over 2 years. Worm intensity ranged from 1 to >1000 worms. Pastured horses were infected more often than non-pastured horses, especially in western Alberta, likely reflecting their higher rates of exposure to mite intermediate hosts. In a comparison of diagnostic techniques, fecal egg counts were the least accurate. Western blot analysis had the highest sensitivity to detect antibodies to the cestode (100%), but had lower specificity. A serological enzyme-linked immunosorbent assay (ELISA) had a lower sensitivity (70%) for detection of antibodies than described in previous studies. A coproantigen ELISA had 74% sensitivity and 92% specificity, and a positive correlation was found between antigen concentration and cestode intensity. The latter is important because it implicates the utility of this method for accurate clinical diagnosis and epidemiological studies.en
dc.identifier.urihttps://hdl.handle.net/10133/681
dc.language.isoen_USen
dc.publisherLethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2008en
dc.publisher.departmentDepartment of Biological Sciencesen
dc.publisher.facultyArts and Scienceen
dc.relation.ispartofseriesThesis (University of Lethbridge. Faculty of Arts and Science)en
dc.subjectDissertations, Academicen
dc.subjectHorses -- Diseasesen
dc.subjectTapewormsen
dc.subjectColic in horsesen
dc.titleEpidemiology and diagnosis of anoplocephala perfoliata in horses from Southern Alberta, Canadaen
dc.typeThesisen
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