Elucidating the role of the DUF 828 gene family of Arabidopsis thaliana in auxin transport

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dc.contributor.authorPrabhakaran Mariyamma, Neema
dc.contributor.authorUniversity of Lethbridge. Faculty of Arts and Science
dc.contributor.supervisorSchultz, Elizabeth
dc.date.accessioned2016-02-17T23:21:44Z
dc.date.available2016-02-17T23:21:44Z
dc.date.issued2015
dc.degree.levelPh.Den_US
dc.description.abstractThe FORKED1 (FKD1) gene encodes a protein with a Domain of Unknown Function (DUF828) and a Pleckstrin Like Domain. The Arabidopsis thaliana genome contains 9 genes with a DUF828 domain whose function has never been characterized. FKD1 localizes to various BFA insensitive post-Golgi compartments and also forms a component of ARF mediated vesicle trafficking, supported by the colocalization of FKD1 with SFC/VAN3 (ARF-GAP) and ARF1 proteins. FKD1 colocalization with PIN1 suggests its role in PIN1 protein trafficking. Several DUF828 family members show colocalization with FKD1 suggesting their possible redundancy in vesicle trafficking pathway. I have identified four genes in the DUF828 family that act redundantly to establish vein meeting in root elongation and root gravitropism in Arabidopsis. PIN1 localization in the developing veins of triple mutants is highly defective indicating the role of the DUF828 family in establishing PIN1 polarity.en_US
dc.embargoNoen_US
dc.identifier.urihttps://hdl.handle.net/10133/4419
dc.language.isoen_CAen_US
dc.proquest.subject0479en_US
dc.proquest.subject0306en_US
dc.proquestyesYesen_US
dc.publisherLethbridge, Alta : University of Lethbridge, Dept. of Biological Sciencesen_US
dc.publisher.departmentDepartment of Biological Sciencesen_US
dc.publisher.facultyFaculty of Arts and Scienceen_US
dc.relation.ispartofseriesThesis (University of Lethbridge. Faculty of Arts and Science)en_US
dc.subjectArabidopsis thalianaen_US
dc.subjectauxin transporten_US
dc.subjectDUF 828 gene familyen_US
dc.subjectleaf vascular formation regulationen_US
dc.subjectPIN1 traffickingen_US
dc.titleElucidating the role of the DUF 828 gene family of Arabidopsis thaliana in auxin transporten_US
dc.typeThesisen_US
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