How the anterior cingulate cortex and the hippocampus represent a decision making task: a population encoding approach

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dc.contributor.authorTomas Cuesta, David Pere
dc.contributor.authorUniversity of Lethbridge. Faculty of Arts and Science
dc.contributor.supervisorGruber, Aaron J.
dc.date.accessioned2021-01-15T18:08:28Z
dc.date.available2021-01-15T18:08:28Z
dc.date.issued2021
dc.degree.levelMastersen_US
dc.description.abstractThe anterior cingulate cortex (ACC) appears to be involved in cognitive control, learning, and memory. Recent proposals integrating these functions suggest that the ACC embodies a cognitive map of task space. In this view, ACC links decision and reward information to particular locations in an abstract map of a task environment, allowing for planning and control. Here, I present novel evidence for task space by showing that, in rats, ACC spatial ensemble activity is preserved when performing a task on a familiar layout, but in a novel spatial context. Furthermore, this encoding similarity is sufficient to decode the animal's position in the new context using the “map” of the familiar layout. I contrast this with hippocampal activity and encoding, which drastically changes when switching spatial contexts. This sheds light into how the brain might encode decision and reinforcement information together with spatial cues to exert top-down control on behavior.en_US
dc.identifier.urihttps://hdl.handle.net/10133/5828
dc.language.isoen_USen_US
dc.proquest.subjectNeurosciences [0317]en_US
dc.proquest.subjectBehavioral psychology [0384]en_US
dc.proquest.subjectBehavioral sciences [0602]en_US
dc.proquestyesYesen_US
dc.publisherLethbridge, Alta. : University of Lethbridge, Dept. of Neuroscienceen_US
dc.publisher.departmentDepartment of Neuroscienceen_US
dc.publisher.facultyArts and Scienceen_US
dc.relation.ispartofseriesThesis (University of Lethbridge. Faculty of Arts and Science)en_US
dc.subjectCognitive neuroscienceen_US
dc.subjectCorpus callosumen_US
dc.subjectDecision makingen_US
dc.subjectDissertations, Academicen_US
dc.subjectHippocampus (Brain)en_US
dc.subjectMemory--Physiological aspectsen_US
dc.subjectNeural networks (Neurobiology)en_US
dc.titleHow the anterior cingulate cortex and the hippocampus represent a decision making task: a population encoding approachen_US
dc.typeThesisen_US
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