The impacts of circadian disruption on hippocampal place cell activity

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dc.contributor.authorRobertson, David R.
dc.contributor.authorUniversity of Lethbridge. Faculty of Arts and Science
dc.contributor.supervisorMcDonald, Robert
dc.date.accessioned2024-07-25T19:45:20Z
dc.date.available2024-07-25T19:45:20Z
dc.date.issued2024
dc.degree.levelMasters
dc.description.abstractCircadian rhythms are daily physiological cycles with wide-reaching influence on biological, mental and behavioural functions. We are at our best when our circadian rhythms function in a stable and consistent manner synchronous with stable and consistent patterns of day and night. Disruptions to circadian rhythms cause all manner of negative effects. One effect that is of particular interest to this study is that spatial memories formed while circadian rhythms are in disarray are not retained as well as those formed in stable conditions. The sorts of memories affected this way have a common factor. They all rely heavily on the hippocampal memory system. Methods have already been devised to read and decipher the neural code of hippocampal place cell firing patterns. However, until now, no attempt has been made to view how circadian disruption influences these hippocampal neural patterns. This experiment bridges that gap.
dc.embargoNo
dc.identifier.urihttps://hdl.handle.net/10133/6828
dc.language.isoen
dc.proquest.subject0317
dc.proquestyesYes
dc.publisherLethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience
dc.publisher.departmentDepartment of Neuroscience
dc.publisher.facultyArts and Science
dc.relation.ispartofseriesThesis (University of Lethbridge. Faculty of Arts and Science)
dc.subjectCircadian
dc.subjectHippocampal
dc.subjectSpatial memories
dc.subjectNeural patterns
dc.subject.lcshCircadian rhythms--Research
dc.subject.lcshDissertations, Academic
dc.titleThe impacts of circadian disruption on hippocampal place cell activity
dc.typeThesis
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