Plasticity in the prefrontal cortex of adult rats
| dc.contributor.author | Kolb, Bryan | |
| dc.contributor.author | Gibb, Robbin L. | |
| dc.date.accessioned | 2016-08-12T22:29:01Z | |
| dc.date.available | 2016-08-12T22:29:01Z | |
| dc.date.issued | 2015 | |
| dc.description | Sherpa Romeo green journal, open access | en_US |
| dc.description.abstract | We review the plastic changes of the prefrontal cortex of the rat in response to a wide range of experiences including sensory and motor experience, gonadal hormones, psychoactive drugs, learning tasks, stress, social experience, metaplastic experiences, and brain injury. Our focus is on synaptic changes (dendritic morphology and spine density) in pyramidal neurons and the relationship to behavioral changes. The most general conclusion we can reach is that the prefrontal cortex is extremely plastic and that the medial and orbital prefrontal regions frequently respond very differently to the same experience in the same brain and the rules that govern prefrontal plasticity appear to differ for those of other cortical regions. | en_US |
| dc.description.peer-review | Yes | en_US |
| dc.identifier.citation | Kolb, B., & Gibb, R. (2015). Plasticity in the prefrontal cortex of adult rats. Frontiers in Cellular Neuroscience, 9(15). doi:10.3389/fncel.2015.00015 | en_US |
| dc.identifier.uri | https://hdl.handle.net/10133/4577 | |
| dc.language.iso | en_CA | en_US |
| dc.publisher | Frontiers Media | en_US |
| dc.publisher.department | Department of Neuroscience | en_US |
| dc.publisher.faculty | Arts and Science | en_US |
| dc.publisher.institution | University of Lethbridge | en_US |
| dc.subject | Prefrontal cortex | en_US |
| dc.subject | Experience-dependent plasticity | en_US |
| dc.subject | Psychoactive drugs | en_US |
| dc.subject | Stress | en_US |
| dc.subject | Metaplasticity | en_US |
| dc.title | Plasticity in the prefrontal cortex of adult rats | en_US |
| dc.type | Article | en_US |