Cannabis and the brain: investigating the long-term effects of high-CBD cannabis exposure on behaviour in the Long-Evans Rat

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dc.contributor.authorNiehaus, Claire
dc.contributor.supervisorKovalchuk, Igor
dc.contributor.supervisorGibb, Robbin L.
dc.date.accessioned2022-01-11T17:08:24Z
dc.date.available2022-01-11T17:08:24Z
dc.date.issued2022
dc.degree.levelMastersen_US
dc.description.abstractCannabis, a drug derived from the plant Cannabis Sativa, is one of the most commonly used drugs worldwide, with a rich history of medicinal application. The increased use of cannabis in recent history has led to a rapid diversification of cannabis strains, each with unique levels of major cannabinoid constituents including tetrahydrocannabinol (THC), the main psychoactive component of cannabis, and cannabidiol (CBD). As social and legislative attitudes towards cannabis begin to change, more people are seeking out this drug for its purported health benefits, many of which are thought to be attributable to CBD. Using four novel high-CBD, low-THC extracts, this research seeks to explore the long-term effects of chronic cannabis exposure on behaviour in a rodent model. Results from this study demonstrate that there are few long-term effects of chronic, high-CBD cannabis exposure on behaviour and that the changes that were observed were not of detriment.en_US
dc.description.sponsorshipNational Sciences and Engineering Research Council of Canada Branch Out Neurological Foundationen_US
dc.identifier.urihttps://hdl.handle.net/10133/6123
dc.language.isoen_USen_US
dc.proquest.subjectNeurosciences [0317]en_US
dc.proquest.subjectBehavioral sciences [0602]en_US
dc.proquest.subjectAnimal sciences [0475]en_US
dc.proquestyesYesen_US
dc.publisherLethbridge, Alta. : University of Lethbridge, Dept. of Neuroscienceen_US
dc.publisher.departmentDepartment of Neuroscienceen_US
dc.publisher.facultyArts and Scienceen_US
dc.relation.ispartofseriesThesis (University of Lethbridge. Faculty of Arts and Science)en_US
dc.subjectBehavioural Neuroscienceen_US
dc.subjectCannabis Researchen_US
dc.subjectDrug Exposureen_US
dc.subjectCannabidiol (CBD)en_US
dc.subjectBehaviouren_US
dc.subjectDissertations, Academicen_US
dc.subjectAnimals -- Drug useen_US
dc.subjectCannabinoidsen_US
dc.subjectCannabisen_US
dc.subjectCannabis -- Health aspectsen_US
dc.subjectNeuropsychiatryen_US
dc.subjectTetrahydrocannabinolen_US
dc.titleCannabis and the brain: investigating the long-term effects of high-CBD cannabis exposure on behaviour in the Long-Evans Raten_US
dc.typeThesisen_US
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