Photocatalytic defluorinative α-aminoalkylation of allylic difluorides

Simple item page
dc.contributor.authorSemeniuk, Taylor
dc.contributor.authorDudas, Ty
dc.contributor.authorOkeh, Esther
dc.contributor.authorFelesky, Tanner
dc.contributor.authorHamel, Jean-Denys
dc.date.accessioned2025-10-30T17:44:52Z
dc.date.available2025-10-30T17:44:52Z
dc.date.issued2024
dc.descriptionAccepted author manuscript
dc.description.abstractA photocatalytic process was devised to synthesize monofluoroalkenes via defluorinative functionalization of allylic difluorides. N-Alkylanilines are used as precursors to α-aminoalkyl radicals, which undergo regioselective addition to allylic difluorides, and subsequent SET and fluoride elimination produce monofluoroalkenes. C–C bond formation on the aniline is site-selective for the least substituted carbon α to nitrogen.
dc.description.peer-reviewYes
dc.identifier.citationSemeniuk, T., Dudas, T., Okeh, E., Felesky, T., & Hamel, J.-D. (2024). Photocatalytic defluorinative α-aminoalkylation of allylic difluorides. Journal of Organic Chemistry, 89(18), 13669-13677. https://doi.org/10.1021/acs.joc.4c01861
dc.identifier.urihttps://hdl.handle.net/10133/7209
dc.language.isoen
dc.publisherACS Publications
dc.publisher.departmentDepartment of Chemistry and Biochemistry
dc.publisher.facultyArts and Science
dc.publisher.institutionUniversity of Lethbridge
dc.publisher.urlhttps://doi.org/10.1021/acs.joc.4c01861
dc.subjectPhotocatalysts
dc.subjectHydrocarbons
dc.subjectChromatography
dc.subjectMolecular structure
dc.subjectCarbon
dc.titlePhotocatalytic defluorinative α-aminoalkylation of allylic difluorides
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Hamel-photocatalytic.pdf
Size:
996.78 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Hamel, Jean-Denys