Escherichia coli O157:H7 lineage persistence and colonization of cattle in vitro

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dc.contributor.authorLowe, Ross M.S.
dc.contributor.authorUniversity of Lethbridge. Faculty of Arts and Science
dc.contributor.supervisorSharma, Ranjana
dc.contributor.supervisorSelinger, L. Brent
dc.date.accessioned2011-08-19T19:20:09Z
dc.date.available2011-08-19T19:20:09Z
dc.date.issued2009
dc.degree.levelMasters
dc.descriptionxiii, 101 leaves ; 29 cmen_US
dc.description.abstractEscherichia coli O157:H7 is an important human pathogen that resides primarily in cattle and feedlot environments. E. coli O157:H7 can be divided into phylogenetic groups termed lineages; lineage I strains are responsible for most human illnesses. An understanding of the etiology of these lineages within cattle and the feedlot environment could allow for more effective surveillance and mitigation strategies. There were no lineage associated differences in growth or survival of E. coli O157:H7 in bovine feces at 4°C, 12°C or 25°C. Lineage I strains more readily colonized cattle jejunum tissue and a bovine colonic cell line than lineage II and intermediate type strains. Enhanced colonization of cattle by lineage I strains may increase the persistence of these strains in feedlots via re-infection and increased shedding. This outcome could increase the transmission of lineage I strains to the food supply and increase the potential for these strains to cause human illness.en_US
dc.identifier.urihttps://hdl.handle.net/10133/2509
dc.language.isoen_USen_US
dc.publisherLethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2009en_US
dc.publisher.departmentDepartment of Biological Sciencesen_US
dc.publisher.facultyArts and Scienceen_US
dc.relation.ispartofseriesThesis (University of Lethbridge. Faculty of Arts and Science)en_US
dc.subjectEscherichia coli O157:H7 -- Researchen_US
dc.subjectCattle -- Pathogens -- Researchen_US
dc.subjectFeedlotsen_US
dc.subjectDissertations, Academicen_US
dc.titleEscherichia coli O157:H7 lineage persistence and colonization of cattle in vitroen_US
dc.typeThesisen_US
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