Chemistry & Biochemistry: Recent submissions

  • Bansal, Akanksha; Karanth, N. Megha; Demeler, Borries; Schindelin, Hermann; Sarma, Siddhartha P. (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryIndian Institute of Science, BangaloreUniversity of Texas Health Science Center at San AntonioUniversity of WeurzburgUniversity of Lethbridgehttps://doi.org/10.1021/acs.biochem.9b00050, 2019)
    Conformational factors that predicate selectivity for valine or isoleucine binding to IlvN leading to the regulation of aceto hydroxy acid synthase I (AHAS I) of Escherichia coli have been determined for the first time ...
  • Salveson, Patrick J.; Haerianardakani, Sepehr; Thuy-Boun, Alexander; Yoo, Stan; Kreutzer, Adam G.; Demeler, Borries; Nowick, James S. (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of California IrvineUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1021/jacs.8b06568, 2018)
    Soluble oligomers of the β-amyloid peptide, Aβ, are associated with the progression of Alzheimer’s disease. Although many small molecules bind to these assemblies, the details of how these molecules interact with Aβ oligomers ...
  • Ranaivoson, Fanomezana M.; Turk, Liam S.; Ozgul, Sinem; Kakehi, Sumie; von Daake, Sventja; Lopez, Nicole; Trobiani, Laura; De Jaco, Antonella; Denissova, Natalia; Demeler, Borries; Özkan, Engin; Montelione, Gaetano T.; Comoletti, Davide (Cell PressArts and ScienceDepartment of Chemistry and BiochemistryChild Health Institute of New JerseySapienza University of RomeRutgers UniversityUniversity of LethbridgeUniversity of Chicagohttps://doi.org/10.1016/j.str.2019.03.004, 2019)
    In the developing brain, cell-surface proteins play crucial roles, but their protein-protein interaction network remains largely unknown. A proteomic screen identified 200 interactions, 89 of which were not previously ...
  • Hu, Jie; Soraiz, Eduardo Hernandez; Johnson, Courtney N.; Demeler, Borries; Brancaleon, Lorenzo (ElsevierArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Texas at San AntonioUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1016/j.ijbiomac.2019.05.060, 2019)
    The evidence that Human Serum Albumin (HSA) binds metal ions and organometallic compounds has generated interest in its physiological role as a metalloprotein and as a vehicle for synthetic biology applications (e.g., ...
  • Demeler, Borries (Portland PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridgehttps://doi.org/10.1042/BIO04102014, 2019)
    In 1926, the Swedish scientist Theodor Svedberg was awarded the Nobel Prize in Chemistry for his work on a disperse system, and for studying the colloidal properties of proteins. This work was, to a ...
  • Kim, Sun Kyung; Barron, Lindsey; Hinck, Cynthia S.; Petrunak, Elyse M.; Cano, Kristin E.; Thangirala, Avinash; Iskra, Brian; Brothers, Molly; Vonberg, Machell; Leal, Belinda; Richter, Blair; Kodali, Ravindra; Taylor, Alexander B.; Du, Shoucheng; Barnes, Christopher O.; Sulea, Traian; Calero, Guillermo; Hart, P. John; Hart, Matthew J.; Demeler, Borries; Hinck, Andrew P. (ASBMB PublicationsArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Pittsburgh School of MedicineUniversity of Texas Health Science Center at San AntonioNational Research Council CanadaUniversity of Lethbridgehttps://doi.org/10.1074/jbc.M116.768754, 2017)
    The transforming growth factor β isoforms, TGF-β1, -β2, and -β3, are small secreted homodimeric signaling proteins with essential roles in regulating the adaptive immune system and maintaining the extracellular matrix. ...
  • Zhang, Jin; Pearson, Joseph Z.; Gorbet, Gary E.; Cölfen, Helmut; Germann, Markus W.; Brinton, Margo A.; Demeler, Borries (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryGeorgia State UniversityUniversity of KonstanzUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1021/acs.analchem.6b03926, 2017)
    Interactions between nucleic acids and proteins are critical for many cellular processes, and their study is of utmost importance to many areas of biochemistry, cellular biology, and virology. Here, we introduce a new ...
  • Tian, Shaoxiong; Yu, Ge; He, Huan; Zhao, Yu; Liu, Peilu; Marshall, Alan G.; Demeler, Borries; Stagg, Scott M.; Li, Hong (Cell PressArts and ScienceDepartment of Chemistry and BiochemistryFlorida State UniversityUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttp://dx.doi.org/10.1016/j.str.2017.08.002, 2017)
    The Saccharomyces cerevisiae (Sc) R2TP complex affords an Hsp90-mediated and nucleotide-driven chaperone activity to proteins of small ribonucleoprotein particles (snoRNPs). The current lack of structural information on ...
  • Nieboer, Jared; Haiges, Ralf; Hillary, William; Yu, Xin; Richardet, Tyler; Mercier, Hélène P. A.; Gerken, Michael (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of LethbridgeUniversity of Southern CaliforniaMcMaster Universityhttps://doi.org/10.1021/ic3005882, 2012)
    The new [N(CH3)4][WSF5] salt was synthesized by two preparative methods: (a) by reaction of WSF4 with [N(CH3)4][F] in CH3CN and (b) directly from WF6 using the new sulfide-transfer reagent [N(CH3)4][SSi(CH3)3]. The ...
  • Johnson, Courtney N.; Gorbet, Gary E.; Ramsower, Heidi; Urquidi, Julio; Brancaleon, Lorenzo; Demeler, Borries (SpringerArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Texas Health Science Center at San AntonioUniversity of Texas at San AntonioUniversity of Lethbridgehttps://doi.org/10.1007/s00249-018-1301-7, 2018)
    The new Beckman Coulter Optima AUC instrument, which features multi-wavelength detection that couples the hydro- dynamic separation of colloidal mixtures to spectral deconvolution of interacting and non-interacting solutes ...
  • Gorbet, Gary E.; Mohapatra, Subhashree; Demeler, Borries (SpringerArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1007/s00249-018-1297-z, 2018)
    A framework for the global analysis of multi-speed analytical ultracentrifugation sedimentation velocity experiments is presented. We discuss extensions to the adaptive space–time finite element fitting methods implemented ...
  • Goettel, James T.; Chaudhary, Praveen; Hazendonk, Paul; Mercier, Hélène P. A.; Gerken, Michael (Royal Society of ChemistryArts and ScienceLibraryUniversity of LethbridgeMcMaster Universityhttps://doi.org/10.1039/C2CC34578A, 2012)
    Sulfur tetrafluoride and triethylamine react at low temperatures to form a 1 : 1 adduct. The unambiguous characterization of the SF4 N(C2H5)3, which is only stable at low temperature, proves the Lewis acid property of ...
  • Goettel, James T.; Turnbull, Douglas; Gerken, Michael (ElsevierArts and ScienceDepartment of Chemistry and BiochemistryUniversity of LethbridgeCanadian Centre for Research in Advanced Fluorine Technologieshttps://doi.org/10.1016/j.jfluchem.2014.07.001, 2015)
    Sulfur tetrafluoride is a reagent for the one-step syntheses of [ReVIIO2F4]−, [IVOF4]−, and [IVIIO2F4]− salts. Pure Ag[ReO2F4] as well as its CH3CN coordination compounds were obtained from CH3CN solvent. The Ag[ReO2F4], ...
  • Chaudhary, Praveen; Bieringer, Mario; Hazendonk, Paul; Gerken, Michael (Royal Society of ChemistryArts and ScienceDepartment of Chemistry and BiochemistryUniversity of LethbridgeCanadian Centre for Research in Advanced Fluorine TechnologiesUniversity of Manitobahttps://doi.org/10.1039/C5DT01994J, 2015)
    The solid-state structure of (CH3)3SnF was reinvestigated by X-ray diffraction techniques as well as by multi-nuclear solid-state NMR spectroscopy. Trimethyltin fluoride crystallizes from hot ethanol in the orthorhombic ...
  • Goettel, James T.; Kostiuk, Nathan; Gerken, MIchael (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of LethbridgeCanadian Centre for Research in Advanced Fluorine Technologieshttps://doi.org/10.1021/acs.inorgchem.6b01112, 2016)
    Adducts between SF4 and a nitrogen base are easily solvolyzed by HF, yielding the protonated nitrogen base and fluoride. Salts resulting from the solvolysis of SF4·NC5H5, SF4·NC5H4(CH3), SF4·NC5H3(CH3)2, and SF4·NC5H4N(CH3)2 ...
  • Majumdar, R. Dutta; Bake, K. D.; Ratna, Y.; Pomerantz, A. E.; Mullins, O. C.; Gerken, Michael; Hazendonk, Paul (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryCanadian Centre for Research in Advanced Fluorine TechnologiesSchlumberger-Doll ResearchUniversity of Lethbridgehttps://doi.org/10.1021/acs.energyfuels.5b02815, 2016)
    Using solid-state 13C NMR spectroscopy of two different asphaltenes, one derived from petroleum and the other from coal liquids, it was shown that the asphaltene molecular architecture consists of a spectrum of sizes, ...
  • Goettel, James T.; Gerken, Michael (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridgehttps://doi.org/10.1021/acs.inorgchem.6b02373, 2016)
    Lewis acid–base adducts between SF4 and the oxygen bases tetrahydrofuran, cyclopentanone, and 1,2-dimethoxyethane were synthesized and characterized by Raman spectroscopy and X-ray crystallography. Crystal structures of ...
  • Williams, Taylor L.; Gorbet, Gary E.; Demeler, Borries (SpringerArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1007/s00249-018-1297-z, 2018)
    A framework for the global analysis of multi-speed analytical ultracentrifugation sedimentation velocity experiments is presented. We discuss extensions to the adaptive space–time finite element fitting methods implemented ...
  • Nelson, Corey R.; Mrozowich, Tyler; Park, Sean M.; D'souza, Simmone; Henrickson, Amy; Vigar, Justin R. J.; Wieden, Hans-Joachim; Owens, Raymond J.; Demeler, Borries; Patel, Trushar R. (MDPIArts and ScienceDepartment of Chemistry and BiochemistryUniversity of LethbridgeUniversity of CalgaryRutherford Appleton LaboratoriesUniversity of MontanaUniversity of Albertahttps://doi.org/10.3390/ijms22010054, 2020)
    Rift Valley fever virus (RVFV) is a mosquito-transmitted virus from the Bunyaviridae family that causes high rates of mortality and morbidity in humans and ruminant animals. Previous studies indicated that DEAD-box helicase ...
  • Turnbull, Douglas; Wetmore, Stacey D.; Gerken, Michael (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryCanadian Centre for Research in Advanced Fluorine TechnologiesUniversity of Lethbridgehttps://doi.org/10.1021/acs.inorgchem.7b02048, 2017)
    Convenient preparative routes to fluorido[(pentafluorophenyl)imido]tungstate(VI) salts have been developed. The reaction of WF6·NC5H5 or [N(CH3)4][WF7] with C6F5NH2 results in quantitative formation of the C5H5NH+ or ...