2026-09-19T02:42:38.206456500Zhttps://opus.uleth.ca/server/oai/requestoai:opus.uleth.ca:10133/1782015-11-05T16:44:57Zcom_10133_3346com_10133_1com_10133_296col_10133_3347col_10133_298
ULethbridge OPUS Repository
supervisor
Whishaw, Ian Q.
author
Harker, Kenneth Troy
author
University of Lethbridge. Faculty of Arts and Science
2007-04-30T21:19:02Z
2007-04-30T21:19:02Z
2002
https://hdl.handle.net/10133/178
Behavioural, electrophysiological, and anatomical evidence suggests that retrosplenial (RS) cortex (areas RSA and RSG) plays a role in spatial navigation. It has been recently suggested that it is damage to the underlying cingulum bundle (CG) (areas CG and IG), and not RS, tht disrupts spatial place learning. I revisited this issue by comparing the rat strains and lesions used in studies that typically report RS deficits, to those used in studies in which no RS deficit is reported. I found both selective RS damage and selective CG damage to disrupt spatial behaviour, suggesting independent contributions to spatial learning and memory from both of these structures. Further, previous failures to find RS deficits are shown to be the result of an inappropriate choice of rat strain for studying normal brain-behaviour relationships combined with a failure to use appropriate testing methods for assessing spatial behaviour.
en_US
Rats -- Behavior
Spatial behavior in animals
Dissertations, Academic
A re-examination of the retrosplenial contribution to place navigation in the rat
Thesis
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URL
http://localhost:4000/bitstreams/2c2fa26c-cf94-4cc3-b6a7-b3fe936dab80/download
File
MD5
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application/pdf
MQ83753.pdf
URL
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File
MD5
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MQ83753.pdf.txt