Browsing Demeler, Borries by Issue Date

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  • Rubio-Marrero, Eva N.; Vincelli, Gabriele; Jeffries, Cy M.; Shaikh, Tanvir R.; Pakos, Irene S.; Ranaivoson, Fanomezana M.; von Daake, Sventja; Demeler, Borries; De Jaco, Antonella; Perkins, Guy; Ellisman, Mark H.; Trewhella, Jill; Comoletti, Davide (ASBMB PublicationsArts and ScienceDepartment of Chemistry and BiochemistryRutgers UniversityUniversity of SydneyMasaryk UniversityUniversity of Texas Health Science Center at San AntonioSapienza University of RomeUniversity of California San DiegoUniversity of UtahUniversity of Lethbridgehttps://doi.org/10.1074/jbc.M115.705681, 2015)
    Contactin-associated protein-like 2 (CNTNAP2) encodes for CASPR2, a multidomain single transmembrane protein belonging to the neurexin superfamily that has been implicated in a broad range of human phenotypes including ...
  • Villarreal, Oscar D.; Chen, Liao Y.; Whetten, Robert L.; Demeler, Borries (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Texas at San AntonioUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1021/acs.jpcb.5b09864, 2015)
    Nanometer-sized gold particles (AuNPs) are of peculiar interest because their behaviors in an aqueous solution are sensitive to changes in environmental factors including the size and shape of the solute ions. In order to ...
  • Alvarez, Marcos M.; Chen, Jenny; Plascencia-Villa, German; Black, David M.; Griffiths, Wendell P.; Garzon, Ignacio L.; Jose-Yacaman, Miguel; Demeler, Borrie; Whetten, Robert L. (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of TexasThermoFisher ScientificUniversidad Nacional Autonoma de MexicoUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1021/acs.jpcb.6b04525, 2016)
    Experimental and theoretical evidence reveals the resilience and stability of the larger aqueous gold clusters protected with p-mercaptobenzoic acid ligands (pMBA) of composition Aun(pMBA)p or (n, p). The Au144(pMBA)60, ...
  • Wong, Sarah J.; Gearhart, Micah D.; Taylor, Alexander B.; Nanyes, David R.; Ha, Daniel J.; Robinson, Angela K.; Artigas, Jason A.; Lee, Oliver J.; Demeler, Borries; Hart, P. John; Bardwell, Vivian J.; Kim, Chongwoo A. (ElsevierArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Texas Health Science Center at San AntonioUniversity of MinnesotaMidwestern UniversitySouth Texas Veterans Health Care SystemUniversity of Lethbridgehttps://doi.org/10.1016/j.str.2016.07.011, 2016)
    KDM2B recruits H2A-ubiquitinating activity of a non-canonical Polycomb Repression Complex 1 (PRC1.1) to CpG islands, facilitating gene repres sion. We investigated the molecular basis of recruit ment using in vitro ...
  • Karabudak, Engin; Brookes, Emre; Lesnyak, Vladimir; Gaponik, Nikolai; Eychmuller, Alexander; Walter, Johannes; Segets, Doris; Peukert, Wolfgang; Wohlleben, Wendel; Demeler, Borries; Colfen, Helmut (WileyArts and ScienceDepartment of Chemistry and BiochemistryMax Planck Institute of Colloids and InterfacesIzmir Institute of TechnologyUniversity of Texas Health Science Center at San AntonioTU DresdenFriedrich-Alexander-Universitat Erlangen-Nurnberg (FAU)BASE SEUniversity of Lethbridgehttps://doi.org/10.1002/anie.201603844, 2016)
    We report an unsurpassed solution characterization technique based on analytical ultracentrifugation, which demonstrates exceptional potential for resolving particle sizes in solution with sub-nm resolution. We achieve ...
  • Ballandras-Colas, Allison; Brown, Monica; Cook, Nicola J.; Dewdney, Tamaria G.; Demeler, Borries; Cherepanov, Peter; Lyumkis, Dmitry; Engelman, Alan N. (Nature PublishingArts and ScienceDepartment of Chemistry and BiochemistryHarvard Medical SchoolThe Salk Institute for Biological StudiesThe Francis Crick InstituteUniversity of Texas Health Science Center at San AntonioImperial College LondonUniversity of Lethbridgehttps://doi.org/10.1038/nature16955, 2016)
    Retroviral integrase catalyses the integration of viral DNA into host target DNA, which is an essential step in the life cycle of all retroviruses1. Previous structural characterization of integrase–viral DNA complexes, ...
  • Smirnova, Ekaterina; Kwan, Jamie J.; Siu, Ryan; Gao, Xin; Zoidl, Georg; Demeler, Borries; Saridakis, Vivian; Donaldson, Logan W. (BioMed CentralArts and ScienceDepartment of Chemistry and BiochemistryYork UniversityKing Abdullah University of Science and TechnologyUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1186/s12964-016-0140-3, 2016)
    CASKIN2 is a homolog of CASKIN1, a scaffolding protein that participates in a signaling network with CASK (calcium/calmodulin-dependent serine kinase). Despite a high level of homology between CASKIN2 and CASKIN1, CASKIN2 ...
  • Gray, Felicia; Cho, Hyo Je; Shukla, Shirish; He, Shihan; Harris, Ashley; Boytsov, Bohdan; Jaremko, Lukasz; Jaremko, Mariusz; Demeler, Borries; Lawlor, Elizabeth R.; Grembecka, Jolanta; Cierpicki, Tomasz (Nature PublishingArts and ScienceDepartment of Chemistry and BiochemistryUniversity of MichiganMax-Planck Institute of Biophysical ChemistryUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1038/ncomms13343, 2016)
    BMI1 is a core component of the polycomb repressive complex 1 (PRC1) and emerging data support a role of BMI1 in cancer. The central domain of BMI1 is involved in protein–protein interactions and is essential for its ...
  • Bhattacharya, Akash; Wang, Zhonghua; White, Tommy; Buffone, Cindy; Nguyen, Laura A.; Shepard, Caitlin N.; Kim, Baek; Demeler, Borries; Diaz-Griffero, Felipe; Ivanov, Dmitri N. (Nature PublishingArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Texas Health Science Center at San AntonioAlbert Einstein College of MedicineEmory School of MedicineKyunghee UniversityUniversity of Lethbridgehttps://doi.org/10.1038/srep31353, 2016)
    SAMHD1, a dNTP triphosphohydrolase, contributes to interferon signaling and restriction of retroviral replication. SAMHD1-mediated retroviral restriction is thought to result from the depletion of cellular dNTP pools, but ...
  • Kim, Sun Kyung; Barron, Lindsey; Hinck, Cynthia S.; Petrunak, Elyse M.; Cano, Kristin E.; Thangirala, Avinash; Iskra, Brian; Brothers, Molly; Vonberg, Machell; Leal, Belinda; Richter, Blair; Kodali, Ravindra; Taylor, Alexander B.; Du, Shoucheng; Barnes, Christopher O.; Sulea, Traian; Calero, Guillermo; Hart, P. John; Hart, Matthew J.; Demeler, Borries; Hinck, Andrew P. (ASBMB PublicationsArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Pittsburgh School of MedicineUniversity of Texas Health Science Center at San AntonioNational Research Council CanadaUniversity of Lethbridgehttps://doi.org/10.1074/jbc.M116.768754, 2017)
    The transforming growth factor β isoforms, TGF-β1, -β2, and -β3, are small secreted homodimeric signaling proteins with essential roles in regulating the adaptive immune system and maintaining the extracellular matrix. ...
  • Zhang, Jin; Pearson, Joseph Z.; Gorbet, Gary E.; Cölfen, Helmut; Germann, Markus W.; Brinton, Margo A.; Demeler, Borries (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryGeorgia State UniversityUniversity of KonstanzUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1021/acs.analchem.6b03926, 2017)
    Interactions between nucleic acids and proteins are critical for many cellular processes, and their study is of utmost importance to many areas of biochemistry, cellular biology, and virology. Here, we introduce a new ...
  • Walter, Johannes; Gorbet, Gary E.; Akdas, Tugce; Segets, Doris; Demeler, Borries; Peukert, Wolfgang (Royal Society of ChemistryArts and ScienceDepartment of Chemistry and BiochemistryFriedrich-Alexander-Universitat Erlangen-Nurnberg (FAU)University of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1039/C6AN02236G, 2017)
    Accurate knowledge of the size, density and composition of nanoparticles (NPs) is of major importance for their applications. In this work the hydrodynamic characterization of polydisperse core–shell NPs by means of ...
  • Tian, Shaoxiong; Yu, Ge; He, Huan; Zhao, Yu; Liu, Peilu; Marshall, Alan G.; Demeler, Borries; Stagg, Scott M.; Li, Hong (Cell PressArts and ScienceDepartment of Chemistry and BiochemistryFlorida State UniversityUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttp://dx.doi.org/10.1016/j.str.2017.08.002, 2017)
    The Saccharomyces cerevisiae (Sc) R2TP complex affords an Hsp90-mediated and nucleotide-driven chaperone activity to proteins of small ribonucleoprotein particles (snoRNPs). The current lack of structural information on ...
  • Fan, Yanlin; Guo, Yusong R.; Yuan, Wang; Zhou, Ying; Holt, Matthew V.; Wang, Tao; Demeler, Borries; Young, Nicolas L.; Zhong, Weiwei; Tao, Yizhi J. (Public Library of ScienceArts and ScienceDepartment of Chemistry and BiochemistryRice UniversityBaylor College of MedicineUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1371/journal.ppat.1006231, 2017)
    Despite the wide use of Caenorhabditis elegans as a model organism, the first virus naturally infecting this organism was not discovered until six years ago. The Orsay virus and its related nematode viruses have a ...
  • Abbott, Jamie A.; Meyer-Schuman, Rebecca; Lupo, Vicenzo; Feeley, Shawna; Mademan, Ines; Oprescu, Stephanie N.; Griffin, Laurie B.; Alberti, M. Antonia; Casasnovas, Carlos; Aharoni, Sharon; Basel-Vanagaite, Lina; Zuchner, Stephan; De Jonghe, Peter; Baets, Jonathan; Shy, Michael E.; Espinos, Carmen; Demeler, Borries; Antonellis, Anthony; Francklyn, Christopher (WileyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of VermontUniversity of Michigan Medical SchoolCentro de Investigacion Principe Felipe (CIPF)University of Iowa Hospitals and ClinicsCenter for Molecular NeurologyInstitute Born-BungeHospital Universitario de BellvitgeTel Aviv UniversitySchneider Children's Medical Center of IsraelRabin Medical CenterUniversity of Miami Miller School of MedicineAntwerp University HospitalUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1002/humu.23380, 2018)
    Histidyl-tRNA synthetase (HARS) ligates histidine to cognate tRNA molecules, which is required for protein translation. Mutations in HARS cause the dominant axonal peripheral neuropathy Charcot-Marie-Tooth disease type 2W ...
  • Salveson, Patrick J.; Haerianardakani, Sepehr; Thuy-Boun, Alexander; Yoo, Stan; Kreutzer, Adam G.; Demeler, Borries; Nowick, James S. (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of California IrvineUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1021/jacs.8b06568, 2018)
    Soluble oligomers of the β-amyloid peptide, Aβ, are associated with the progression of Alzheimer’s disease. Although many small molecules bind to these assemblies, the details of how these molecules interact with Aβ oligomers ...
  • Sterritt, Oliver W.; Lang, Eric J. M.; Kessans, Sarah A.; Ryan, Timothy M.; Demeler, Borries; Jameson, Geoffrey B.; Parker, Emily J. (Portland PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of CanterburyUniversity of AucklandAustralian Synchrotron/ANSTOUniversity of LethbridgeMassey UniversityVictoria University of Wellingtonhttps://doi.org/10.1042/BSR20181605, 2018)
    In Pseudomonas aeruginosa ( Pae ), the shikimate pathway end product, chorismate, serves as the last common precursor for the biosynthesis of both primary aromatic metabolites, including phenylalanine, tyrosine and tryptophan, ...
  • Kim, Haram; Brookes, Emre; Cao, Weiming; Demeler, Borries (SpringerArts and ScienceDepartment of Chemistry and BiochemistryCornell UniversityUniversity of Texas Health Science Center at San AntonioUniversity of Texas at San AntonioUniversity of Lethbridgehttps://doi.org/10.1007/s00249-018-1309-z, 2018)
    Sedimentation velocity experiments performed in the analytical ultracentrifuge are modeled using finite-element solutions of the Lamm equation. During modeling, three fundamental parameters are optimized: the sedimentation ...
  • Wagner, Jonathan M.; Christensen, Devin E.; Bhattacharya, Akash; Dawidziak, Daria M.; Roganowicz, Marcin D.; Wan, Yueping; Pumroy, Ruth A.; Demeler, Borries; Ivanov, Dmitri N.; Ganser-Pornillos, Barbie K.; Sundquist, Wesley I.; Pornillos, Owen (American Society for MicrobiologyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of VirginiaUniversity of UtahUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1128/JVI.01563-17, 2018)
    Restriction factors are intrinsic cellular defense proteins that have evolved to block microbial infections. Retroviruses such as HIV-1 are restricted by TRIM5 proteins, which recognize the viral capsid shell that surrounds, ...
  • Lopez, Priscilla; Lara, Humberto H.; Mullins, Sean M.; Black, David M.; Ramsower, Heidi M.; Alvarez, Marcos M.; Williams, Tayler L.; Lopez-Lozano, Xochitl; Weissker, Hans-Christian; Garcia, A. Patricio; Garzon, Ignacio L.; Demeler, Borries; Lopez-Ribot, Jose Luis; Yacaman, Miguel J.; Whetten, Robert L. (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of TexasUniversity of Texas Health Science Center at San AntonioAix Marseille UniversityUniversidad Nacional Autonoma de MexicoUniversity of Lethbridgehttps://doi.org/10.1021/acsanm.8b00069, 2018)
    Here we report on the identification and applications of an aqueous 29-atom silver cluster stabilized with 12 lipoate ligands, i.e. Ag29(R-α–LA)12 or (29,12), wherein R-α–LA = R-α-lipoic acid, a natural dithiolate. Its ...