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dc.contributor.author Lansink, Carien S.
dc.contributor.author Goltstein, Pieter M.
dc.contributor.author Lankelma, Jan V.
dc.contributor.author McNaughton, Bruce L.
dc.contributor.author Pennartz, Cyriel M. A.
dc.date.accessioned 2017-02-28T23:46:28Z
dc.date.available 2017-02-28T23:46:28Z
dc.date.issued 2009
dc.identifier.citation Lansink, C. S., Golstein, P. M., Lankelma, J. V., McNaughton, B. L., & Pennartz, C. M. A. (2009). Hippocampus leads ventral stiatum in reply of place-reward information. PLoS Biology, 7(8): e1000173. doi:10.1371/journal.pbio.1000173 en_US
dc.identifier.uri https://hdl.handle.net/10133/4786
dc.description Sherpa Romeo green journal: open access en_US
dc.description.abstract Associating spatial locations with rewards is fundamental to survival in natural environments and requires the integrity of the hippocampus and ventral striatum. In joint multineuron recordings from these areas, hippocampal–striatal ensembles reactivated together during sleep. This process was especially strong in pairs in which the hippocampal cell processed spatial information and ventral striatal firing correlated to reward. Replay was dominated by cell pairs in which the hippocampal ‘‘place’’ cell fired preferentially before the striatal reward-related neuron. Our results suggest a plausible mechanism for consolidating place-reward associations and are consistent with a central tenet of consolidation theory, showing that the hippocampus leads reactivation in a projection area. en_US
dc.language.iso en_US en_US
dc.publisher Public Library of Science en_US
dc.subject Hippocampus (Brain) en_US
dc.subject Ventral striatum en_US
dc.subject Place-reward associations en_US
dc.subject Sleep en_US
dc.title Hippocampus leads ventral striatum in reply of place-reward information en_US
dc.type Article en_US
dc.publisher.faculty Arts and Science en_US
dc.publisher.department Department of Neuroscience en_US
dc.description.peer-review Yes en_US
dc.publisher.institution University of Amsterdam en_US
dc.publisher.institution University of Lethbridge en_US


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