Browsing Kolb, Bryan by Title

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  • Manitt, C.; Eng, C.; Pokinko, M.; Ryan, R. T.; Torres-Berrio, A.; Lopez, J. P.; Yogendran, S. V.; Daubaras, M. J. J.; Grant, A.; Schmidt, E. R. E.; Tronche, F.; Krimpenfort, P.; Cooper, H. M.; Pasterkamp, R. J.; Kolb, Bryan; Turecki, G.; Wong, T. P.; Nestler, E. J.; Giros, B.; Flores, C. (Macmillan PublishersArts and ScienceDepartment of NeuroscienceMcGill UniversityUniversity Medical Center UtrechtUniversite Pierre et Marie CurieThe Netherlands Cancer InstituteUniversity of QueenslandUniveristy of LethbridgeMount Sinai School of Medicine, 2013)
    Adolescence is a period of heightened susceptibility to psychiatric disorders of medial prefrontal cortex (mPFC) dysfunction and cognitive impairment. mPFC dopamine (DA) projections reach maturity only in early adulthood, ...
  • Kolb, Bryan; Teskey, G. Campbell; Gibb, Robbin L. (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeUniversity of Calgary, 2010)
    An important development in behavioral neuroscience in the past 20 years has been the demonstration that it is possible to stimulate functional recovery after cerebral injury in laboratory animals. Rodent models of ...
  • Kovalchuk, Anna; Ilnytskyy, Yaroslav; Rodriquez-Juarez, Rocio; Katz, Amanda; Sidransky, David; Kolb, Bryan; Kovalchuk, Olga (Impact JournalsArts and ScienceDepartment of Biological SciencesDepartment of NeuroscienceUniversity of LethbridgeChampions OncologyUniversity of Calgary, 2017)
    A wide array of central nervous system complications, neurological deficits, and cognitive impairments occur and persist as a result of systemic cancer and cancer treatments. This condition is known as chemo brain and it ...
  • Kolb, Bryan; Muhammad, Arif (Frontiers MediaArts and ScienceDepartment of NeuroscienceUniversity of Lethbridge, 2014)
    A fundamental property of the brain is its capacity to change with a wide variety of experiences, including injury. Although there are spontaneous reparative changes following injury, these changes are rarely sufficient ...
  • Hehar, Harleen; Yeates, Keith; Kolb, Bryan; Esser, Michael J.; Mychasiuk, Richelle (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of CalgaryUniversity of Lethbridge, 2015)
    Impulsivity and poor executive control have been implicated in the pathogenesis of many developmental and neuropsychiatric disorders. Similarly, concussions/mild traumatic brain injuries (mTBI) have been associated with ...
  • Kovalchuk, Anna; Mychasiuk, Richelle; Muhammad, Arif; Hossain, Shakhawat; Ilnytskyy, Slava; Ghose, Abhijit; Kirby, Charles; Ghasroddashti3, Esmaeel; Kovalchuk, Olga; Kolb, Bryan (Impact JournalsArts and ScienceDepartment of Biological SciencesDepartment of NeuroscienceUniversity of LethbridgeAlberta Health ServicesUniversity of CalgaryAlberta Epigenetics NetworkCanadian Institute for Advanced Research, 2016)
    Radiation therapy can not only produce effects on targeted organs, but can also influence shielded bystander organs, such as the brain in targeted liver irradiation. The brain is sensitive to radiation exposure, and ...
  • Milstein, Jean A.; Elnabawi, Ahmed; Vinish, Monika; Swanson, Thomas; Enos, Jennifer K.; Bailey, Aileen M.; Kolb, Bryan; Frost, Douglas O. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of Maryland School of MedicineSt. Mary's College of MarylandUniversity of Lethbridge, 2013)
    Antipsychotic drugs are increasingly used in children and adolescents to treat a variety of psychiatric disorders. However, little is known about the long-term effects of early life antipsychotic drug treatment. Most ...
  • Kolb, Bryan; Gibb, Robbin L. (Frontiers MediaArts and ScienceDepartment of NeuroscienceUniversity of Lethbridge, 2015)
    We review the plastic changes of the prefrontal cortex of the rat in response to a wide range of experiences including sensory and motor experience, gonadal hormones, psychoactive drugs, learning tasks, stress, social ...
  • Gibb, Robbin L.; Gonzalez, Claudia L. R.; Kolb, Bryan (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of Lethbridge, 2014)
    Birth is a particularly vulnerable time for acquiring brain injury. Unfortunately, very few treatments are available for those affected. Here we explore the effectiveness of prenatal intervention in an animal model of early ...
  • Kovalchuk, Anna; Mychasiuk, Richelle; Muhammad, Arif; Hossain, Shakhawat; Ilnytskyy, Yaroslav; Ghose, Abhijit; Kirkby, Charles; Ghasroddashti, Esmaeel; Kolb, Bryan; Kovalchuk, Olga (Frontiers MediaArts and ScienceDepartment of NeuroscienceDepartment of Biological SciencesUniversity of LethbridgeAlberta Epigenetics NetworkUniversity of CalgaryAlberta Health ServicesCanadian Institute for Advanced Research, 2016)
    Irradiated cells can signal damage and distress to both close and distant neighbors that have not been directly exposed to the radiation (naïve bystanders). While studies have shown that such bystander effects occur in the ...