Browsing Kovalchuk, Olga by Title

Sort by: Order: Results:

  • Zucchi, Fabiola C. R.; Yao, Youli; Ward, Isaac D.; Ilnytskyy, Yaroslav; Olson, David M.; Benzies, Karen; Kovalchuk, Igor; Kovalchuk, Olga; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceDepartment of Biological SciencesUniversity of LethbridgeUniversity of Mato Grosso StateUniversity of AlbertaUniversity of Calgary, 2013)
    The gestational state is a period of particular vulnerability to diseases that affect maternal and fetal health. Stress during gestation may represent a powerful influence on maternal mental health and offspring brain ...
  • Krishnan, Preethi; Ghosh, Sunita; Wang, Bo; Li, Dongping; Narasimhan, Ashok; Berendt, Richard; Graham, Kathryn; Mackey, John R.; Kovalchuk, Olga; Damaraju, Sambasivarao (BioMed CentralArts and ScienceDepartment of Biological SciencesUniversity of AlbertaCross Cancer InstituteUniversity of Lethbridge, 2015)
    Background: Prognostication of Breast Cancer (BC) relies largely on traditional clinical factors and biomarkers such as hormone or growth factor receptors. Due to their suboptimal specificities, it is challenging to ...
  • Lezhnina, Ksenia; Kovalchuk, Olga; Zhavoronkov, Alexander A.; Korzinkin, Mikhail B.; Zabolotneva, Anastasia A.; Shegay, Peter V.; Sokov, Dmitry G.; Gaifullin, Nurshat M.; Rusakov, Igor G.; Aliper, Alexander M.; Roumiantsev, Sergey A.; Alekseev, Boris Y.; Borisov, Nikolay M.; Buzdin, Anton A. (Impact JournalsArts and ScienceDepartment of Biological SciencesPathway PharmaceuticalsD. Rogachyov Federal Research Center of Pediatric Hematology, Oncology and ImmunologyUniversity of LethbridgeCanada Cancer and Aging Research Laboratories Ltd.John Hopkins UniversityMoscow Institute of Physics and TechnologyShemyakn-Ovchinnikov Institute of Bioorganic ChemistryP.A. Herzen Moscow Oncological Research InstituteMoscow 1st Oncological HospitalLomonosov Moscow State UniversityRussian Medical Postgraduate AcademyA.I. Burnasyan Federal Medical Biophysical Center, 2014)
    We recently proposed a new bioinformatic algorithm called OncoFinder for quantifying the activation of intracellular signaling pathways. It was proved advantageous for minimizing errors of high-throughput gene expression ...
  • Krishnan, Preethi; Ghosh, Sunita; Graham, Kathryn; Mackey, John R.; Kovalchuk, Olga; Damaraju, Sambasivarao (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of AlbertaAlberta Health ServicesUniversity of Lethbridge, 2016)
    Piwi-interacting RNAs (piRNAs), whose role in germline maintenance has been established, are now also being classified as post-transcriptional regulators of gene expression in somatic cells. PIWI proteins, central to piRNA ...
  • Krishnan, Preethi; Ghosh, Sunita; Wang, Bo; Heyns, Mieke; Graham, Kathryn; Mackey, John R.; Kovalchuk, Olga; Damaraju, Sambasivarao (Public Library of ScienceArts and ScienceDepartment of Biological SciencesUniversity of Lethbridge, 2016)
    One of the most abundant,yet least explored,classes of RNA is the small nucleolar RNAs (snoRNAs), which are well known for their involvement in post-transcriptional modifications of other RNAs. Although snoRNAs were only ...
  • Kovalchuk, Anna; Mychasiuk, Richelle; Muhammad, Arif; Hossain, Shakhawat; Ilnytskyy, Yaroslav; Ghose, Abhijit; Kirkby, Charles; Ghasroddashti, Esmaeel; Kolb, Bryan; Kovalchuk, Olga (Frontiers MediaArts and ScienceDepartment of NeuroscienceDepartment of Biological SciencesUniversity of LethbridgeAlberta Epigenetics NetworkUniversity of CalgaryAlberta Health ServicesCanadian Institute for Advanced Research, 2016)
    Irradiated cells can signal damage and distress to both close and distant neighbors that have not been directly exposed to the radiation (naïve bystanders). While studies have shown that such bystander effects occur in the ...
  • Wang, Bo; Li, Dongping; Sidler, Corinne; Rodriquez-Juarez, Rocio; Singh, Natasha; Heyns, Mieke; Ilnytskyy, Yaroslav; Bronson, Roderick T.; Kovalchuk, Olga (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of LethbridgeQiqihar Medical UniversityThe Dana Farber/Harvard Comprehensive Cancer Center, 2015)
    Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related deaths worldwide, and it has been linked to radiation exposure. As a well-defined oncogene, wild-type p53-induced phosphatase 1 (WIP1) plays ...
  • Singhal, Sandeep K.; Usmani, Nawaid; Michiels, Stefan; Metzger-Filho, Otto; Saini, Kamal S.; Kovalchuk, Olga; Parliament, Matthew (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of AlbertaService de Biostatistique et d'EpidemiologieUniversité Paris-SudHarvard Medical SchoolQuantum Health Analytics SPRLUniversity of LethbridgeCanada Cancer and Aging Research Laboratories Ltd., 2016)
    Until recently, an elevated disease risk has been ascribed to a genetic predisposition, however, exciting progress over the past years has discovered alternate elements of inheritance that involve epigenetic regulation. ...
  • Kovalchuk, Igor; Kovalchuk, Olga (M D P I A GArts and ScienceDepartment of Biological SciencesUniversity of Lethbridge, 2008)
    Rapid technological development is inevitably associated with many environmental problems which primarily include pollution of soil, water and air. In many cases, the presence of contamination is difficult to assess. It ...