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dc.contributor.supervisor Kolb, Bryan
dc.contributor.author Williams, Preston T.J.A.
dc.contributor.author University of Lethbridge. Faculty of Arts and Science
dc.date.accessioned 2016-02-27T19:30:33Z
dc.date.available 2016-02-27T19:30:33Z
dc.date.issued 2009
dc.identifier.uri https://hdl.handle.net/10133/4434
dc.description.abstract In Canada, every ten minutes someone will have a stroke injury to the brain. According to the Heart and Stroke Foundation of Canada 15% of the patients will die and only 10% of patients will recover normal behaviour completely. The remaining 75% of stroke patients will experience one or many cognitive and motor neurological deficits. This thesis examines a rat model of human perinatal stroke populations most at risk to study the long-term behavioural, neurophysiological, and anatomical outcomes in maturity. Evidence is provided showing that the nature of motor deficits is dependent on the age- of-stroke and earlier ages do not lead to better outcomes. These data are important because they show that motor learning requires an optimal organization of the motor cortex to support motor behaviours. Early experiences, such as a stroke, can impair motor skills and the organization and function of the motor system in adulthood. en_US
dc.language.iso en_CA en_US
dc.publisher Lethbridge, Alta. : University of Lethbridge, Department of Neuroscience en_US
dc.relation.ispartofseries Thesis (University of Lethbridge. Faculty of Arts and Science) en_US
dc.subject perinatal stroke en_US
dc.subject rat model en_US
dc.subject motor-deficits en_US
dc.subject drug treatment evaluation en_US
dc.subject motor maps en_US
dc.subject behaviour-brain plasticity en_US
dc.subject neonatal hypoxic ischemia en_US
dc.title Neonatal stroke in rats impairs behaviour, anatomy, and neurophysiology in adulthood en_US
dc.type Thesis en_US
dc.publisher.faculty Arts and Science en_US
dc.publisher.department Department of Neuroscience en_US
dc.degree.level Ph.D en_US
dc.proquestyes No en_US
dc.embargo No en_US


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