Faculty Research and Publications: Recent submissions

  • Becke, A. D.; Roussel, Marc R. (American Physical SocietyArts and ScienceDepartment of Chemistry and BiochemistryQueen's UniversityUniversity of Lethbridgehttps://doi.org/10.1103/PhysRevA.39.3761, 1989)
    We present a new coordinate-space model of spherically averaged exchange-hole functions in inhomogeneous systems that depends on local values of the density and its gradient and Laplacian, and also the kinetic energy ...
  • Beekman, Richard A.; Roussel, Marc R.; Wilson, P. J. (American Physical SocietyArts and ScienceDepartment of Chemistry and BiochemistryDepartment of PhysicsUniversity of Lethbridgehttps://doi.org/10.1103/PhysRevA.59.503, 1999)
    We have computed the equilibrium conformations of clusters of up to 100 ions in a spherically symmetric harmonic trap by a simple optimization strategy called seeding in which ions are added or removed from ...
  • Roussel, Marc R.; Wang, Jichang (American Physical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridgehttps://doi.org/10.1103/PhysRevLett.87.188302, 2001)
    In this Letter, we report the observation of a transition from self-replicating behavior to stationary spatial structures induced by concentration-dependent diffusivities in the excitable Gray-Scott medium. Notably, the ...
  • Closson, Taunia L. L.; Roussel, Marc R. (American Physical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridgehttps://doi.org/10.1103/PhysRevLett.85.3974, 2000)
    Many natural and technological systems have on/off switches. For instance, mitosis can be halted by biochemical switches which act through the phosphorylation state of a complex called mitosis promoting factor. If switching ...
  • Juranek, Stefan; Wieden, Hans-Joachim; Lipps, Hans J. (Oxford University PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Witten/HerdeckeUniversity of Lethbridgehttps://doi.org/10.1093/nar/gkg233, 2003)
    Dramatic DNA reorganization and elimination processes occur during macronuclear differentiation in ciliates. In this study we analyzed whether cytosine methylation of specific sequences plays a functional role during DNA ...
  • Gu, Shan-Qing; Peske, Frank; Wieden, Hans-Joachim; Rodnina, Marina V.; Wintermeyer, Wolfgang (Cold Springs Harbor Laboratory PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Witten/HerdeckeUniversity of Lethbridge, 2003)
    The signal recognition particle (SRP) from Escherichia coli, composed of Ffh protein and 4.5S RNA, mediates membrane targeting of translating ribosomes displaying a signal or signal-anchor sequence. SRP binds at the peptide ...
  • Armstrong, A.; Chivers, T.; Boeré, René T. (American Chemical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of CalgaryUniversity of Lethbridge, 2005)
    Stable and persistent phosphorus-containing radicals can be divided into five general categories: phosphinyl, diphosphanyl, 1,3-diphosphaallyl, lithiated tetrakisimidophosphates, and phosphaverdazyl systems. The syntheses, ...
  • Beal, Jacob; Haddock-Angelli, Traci; Gershater, Markus; De Mora, Kim; Lizarazo, Meagan; Hollenhorst, Jim; Rettberg, Randy; iGEM Interlab Study Contributors (Public Library of ScienceArts and ScienceDepartment of Chemistry and BiochemistryRaytheon BBN TechnologiesiGEM FoundationSynthaceAgilentUniversity of Lethbridge, 2016)
    We present results of the first large-scale interlaboratory study carried out in synthetic biology, as part of the 2014 and 2015 International Genetically Engineered Machine (iGEM) competitions. Participants at 88 institutions ...
  • De Laurentiis, Evelina I.; Girodat, Dylan J.; Mercier, Evan; Wieden, Hans-Joachim (Biomath ForumArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2016)
    Translation, the ribosome dependent synthesis of proteins, is the last step of gene expression. It is targeted by a large number of antibiotics that modulate, in one way or the other, the dynamic properties of the involved ...
  • Roussel, Marc R.; Lloyd, David (Arts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2007)
  • Roussel, Catharine J.; Roussel, Marc R. (Arts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2003)
  • Beekman, Richard A.; Roussel, Marc R.; Wilson, P. J. (Arts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 1999)
  • Roussel, Marc R. (Biomath ForumArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2013)
    A previously studied model of prokaryotic transcription [Roussel and Zhu, Bull. Math. Biol. 68 (2006) 1681--1713] is revisited. The first four moments of the distribution of transcription times are obtained analytically ...
  • Thibault, Michelle E.; Parvez, Masood; Dibble, Peter W. (International Union of CrystallographyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of LethbridgeUniversity of Calgary, 2008)
    The title compound, C25H18N2O6, is a naphthalenophane styled in the manner of Warrener's alicyclic cyclo­phanes or mol­ecular racks wherein a trimethyl­ene tether is perfectly staggered between the two N atoms such that ...
  • Wright, Jaden R.; Keffer-Wilkes, Laura C.; Dobing, Selina R.; Wieden-Kothe, Ute (Cold Springs Harbor Laboratory PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2011)
    Pseudouridine synthases catalyze formation of the most abundant modification of functional RNAs by site-specifically isomerizing uridines to pseudouridines. While the structure and substrate specificity of these enzymes ...
  • Tillault, Anne-Sophie; Fourmann, Jean-Baptiste; Loegler, Christine; Wieden, Hans-Joachim; Wieden-Kothe, Ute; Charpentier, Bruno (Cold Spring Harbor Laboratory PressArts and ScienceDepartment of Chemistry and BiochemistryBipole de l'Université de LorraineUniversity of Lethbridge, 2015)
    In all organisms, several distinct stand-alone pseudouridine synthase (PUS) family enzymes are expressed to isomerizeuridine into pseudouridine (Ψ) by specific recognition of RNAs. In addition, Ψs are generated in Archaea ...
  • Roussel, Catharine J.; Roussel, Marc R. (ElsevierArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge10.1016/j.biosystems.2018.10.003, 2018)
    The expression of the TGF-β protein Nodal on the left side of vertebrate embryos is a determining event in the development of internal-organ asymmetry. We present a mathematical model for the control of the expression of ...
  • Boeré, René T. (Royal Society of ChemistryArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2013)
    [No abstract available]
  • Marszaukowskia, Flávia; Guimarãesa, Ivelise Dimbarre Lao; da Silvaa, Juliana Paula; da Silveira Lacerda, Luis Henrique; de Lazaroa, Sergio Ricardo; de Araujob, Márcio Peres; Castellena, Patrícia; Tominaga, Tania Toyomi; Boeré, René T.; Wohnrath, Karen (ElsevierArts and ScienceDepartment of Chemistry and BiochemistryUniversidade Estadual de Ponta GrossaUniversidade Federal do ParanáUniversidade Estadual do Centro-OesteUniversity of Lethbridge, 2019)
    The synthesis and spectroscopic characterization of four ruthenium(II) arene complexes with monodentate pyridine derivatives ([( 6–p-cymene)RuCl2L]: L = 2-aminopyridine, 2-methylaminopyridine, 2-benzylaminopyridine, and ...
  • Begum, Imtiaz; Schnakenburg, Gregor; Kelemen, Zsolt; Nyulászi, Laszlo; Boeré, René T.; Streubel, Rainer (Royal Society of ChemistryArts and ScienceDepartment of Chemistry and BiochemistryInstitut für Anorganische Chemie der Rheinischen Friedrich-Wilhelms-Universität BonnBudapest University of Technology and EconomicsMTA-BME Computation Driven Chemistry ResearchUniversity of Lethbridge, 2018)
    A new sulfur-enriched tricyclic 1,4-diphosphinine (2) was synthesized and novel reactivity studies on the phosphorus heterocycle was performed: A weak anionic nucleophile (KHMDS) adds selectively thus forming a stable ...