Browsing Faculty Research and Publications by Subject "Ribosome"

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  • Coatham, Mackenzie L.; Brandon, Harland E.; Fischer, Jeffrey J.; Schummer, Tobias; Wieden, Hans-Joachim (Oxford University PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of AlbertaUniversity of Lethbridgehttps://doi.org/10.1093/nar/gkv1524, 2016)
    Using a combination of biochemical, structural probing and rapid kinetics techniques we reveal for the first time that the universally conserved translational GTPase (trGTPase) HflX binds to the E-site of the 70S ribosome ...
  • Shank, Roxanne A.; Foroud, Nora A.; Hazendonk, Paul; Eudes, François; Blackwell, Barbara A. (M D P I A GArts and ScienceDepartment of Chemistry & BiochemistryAgriculture and Agri-Food CanadaUniversity of Lethbridge, 2011)
    Fungal toxins, such as those produced by members of the order Hypocreales, have widespread effects on cereal crops, resulting in yield losses and the potential for severe disease and mortality in humans and livestock. ...
  • Chaudhary, Praveen; Shank, Roxanne A.; Montina, Tony; Goettel, James T.; Foroud, Nora A.; Hazendonk, Paul; Eudes, François (M D P I A GArts and ScienceDepartment of Chemistry & BiochemistryUniversity of LethbridgeAgriculture and Agri-Food Canada, 2011)
    The structure of T-2 toxin in the solid-state is limited to X-ray crystallographic studies, which lack sufficient resolution to provide direct evidence for hydrogen-bonding interactions. Furthermore, its solution-structure, ...