Browsing Faculty Research and Publications by Title

Sort by: Order: Results:

  • Roussel, Marc R. (Biomath ForumArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2013)
    A previously studied model of prokaryotic transcription [Roussel and Zhu, Bull. Math. Biol. 68 (2006) 1681--1713] is revisited. The first four moments of the distribution of transcription times are obtained analytically ...
  • Wright, Jaden R.; Keffer-Wilkes, Laura C.; Dobing, Selina R.; Wieden-Kothe, Ute (Cold Springs Harbor Laboratory PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2011)
    Pseudouridine synthases catalyze formation of the most abundant modification of functional RNAs by site-specifically isomerizing uridines to pseudouridines. While the structure and substrate specificity of these enzymes ...
  • Maaninen, Arto; Boeré, René T.; Chivers, Tristram; Parvez, Masood (Verlag der Zeitschrift für NaturforschungArts and ScienceDepartment of Chemistry and BiochemistryUniversity of OuluUniversity of LethbridgeUniversity of Calgary, 1999)
    The reaction of SeCU or SeCF with /V,/V’-bis(trimethylsilyl)-2,6-diisopropylaniline occurs not at the nitrogen atom but by electrophilic aromatic substitution at C-4 of the phenyl ring to give [(CH3)3Si]2NC6H2('Pr:)SeCl3, ...
  • Beal, Jacob; Haddock-Angelli, Traci; Gershater, Markus; De Mora, Kim; Lizarazo, Meagan; Hollenhorst, Jim; Rettberg, Randy; iGEM Interlab Study Contributors (Public Library of ScienceArts and ScienceDepartment of Chemistry and BiochemistryRaytheon BBN TechnologiesiGEM FoundationSynthaceAgilentUniversity of Lethbridge, 2016)
    We present results of the first large-scale interlaboratory study carried out in synthetic biology, as part of the 2014 and 2015 International Genetically Engineered Machine (iGEM) competitions. Participants at 88 institutions ...
  • Marszaukowskia, Flávia; Guimarãesa, Ivelise Dimbarre Lao; da Silvaa, Juliana Paula; da Silveira Lacerda, Luis Henrique; de Lazaroa, Sergio Ricardo; de Araujob, Márcio Peres; Castellena, Patrícia; Tominaga, Tania Toyomi; Boeré, René T.; Wohnrath, Karen (ElsevierArts and ScienceDepartment of Chemistry and BiochemistryUniversidade Estadual de Ponta GrossaUniversidade Federal do ParanáUniversidade Estadual do Centro-OesteUniversity of Lethbridge, 2019)
    The synthesis and spectroscopic characterization of four ruthenium(II) arene complexes with monodentate pyridine derivatives ([( 6–p-cymene)RuCl2L]: L = 2-aminopyridine, 2-methylaminopyridine, 2-benzylaminopyridine, and ...
  • Aon, Miguel A.; Roussel, Marc R.; Cortassa, Sonia; O'Rourke, Brian; Murray, Douglas B.; Beckmann, Manfred; Lloyd, David (Public Library of ScienceArts and ScienceDepartment of Chemistry and BiochemistryJohns Hopkins University Institute of Molecular CardiobiologyUniversity of LethbridgeKeio UniversityUniversity of WalesCardiff University, 2008)
    Temporal organization of biological processes requires massively parallel processing on a synchronized time-base. We analyzed time-series data obtained from the bioenergetic oscillatory outputs of Saccharomyces cerevisiae ...
  • Boeré, René T. (Royal Society of ChemistryArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2016)
    The structure of dimeric 2,7-bisij4-(trifluoromethyl)phenyl]-4λ4,5λ4,9λ4,10λ4-tetrathietoij1,2-a:3,4-a′]bis [1,2,3,5]dithiadiazole (C8H4F3N2S2)2 and its adduct with triphenylstibin (C8H4F3N2S2)2·C18H15Sb, both have triclinic ...
  • Gu, Shan-Qing; Peske, Frank; Wieden, Hans-Joachim; Rodnina, Marina V.; Wintermeyer, Wolfgang (Cold Springs Harbor Laboratory PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Witten/HerdeckeUniversity of Lethbridge, 2003)
    The signal recognition particle (SRP) from Escherichia coli, composed of Ffh protein and 4.5S RNA, mediates membrane targeting of translating ribosomes displaying a signal or signal-anchor sequence. SRP binds at the peptide ...
  • Foroud, Nora A.; Shank, Roxanne A.; Kiss, Douglas; Eudes, François; Hazendonk, Paul (Frontiers MediaArts and ScienceDepartment of Chemistry and BiochemistryLethbridge Research and Development CentreUniversity of Lethbridge, 2016)
    Fusarium head blight (FHB) is a disease of cereal crops caused by trichothecene producing Fusarium species. Trichothecenes, macrocylicic fungal metabolites composed of three fused rings (A–C) with one epoxidef unctionality, ...
  • Gruninger, Robert J.; Thibault, John; Capeness, Michael J.; Till, Robert; Mosimann, Steven C.; Sockett, R. Elizabeth; Selinger, L. Brent; Lovering, Andrew L. (Public Library of ScienceArts and ScienceDepartment of Biological SciencesDepartment of Chemistry and BiochemistryLethbridge Research and Development CentreUniversity of NottinghamUniversity of LethbridgeUniversity of Birmingham, 2014)
    Bdellovibrio bacteriovorus is an unusual d-proteobacterium that invades and preys on other Gram-negative bacteria and is of potential interest as a whole cell therapeutic against pathogens of man, animals and crops. PTPs ...
  • Sproviero, Michael; Verwey, Anne M. R.; Rankin, Katherine M.; Witham, Aaron A.; Soldatov, Dmitriy V.; Manderville, Richard A.; Fekry, Mostafa I.; Sturla, Shana J.; Sharma, Purshotam; Wetmore, Stacey D. (Oxford University PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of GuelphInstitute of Food, Nutrition and Health (Switzerland)Cairo UniversityUniversity of Lethbridge, 2014)
    Chemical mutagens with an aromatic ring system may be enzymatically transformed to afford aryl radical species that preferentially react at the C8-site of 2 -deoxyguanosine (dG). The resulting carbonlinked C8-aryl-dG ...
  • Sharma, Purshotam; Manderville, Richard A.; Wetmore, Stacey D. (Oxford University PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of LethbridgeUniversity of Guelph, 2014)
    The nephrotoxic food mutagen ochratoxin A (OTA) produces DNA adducts in rat kidneys, the major lesion being the C8-linked-2 -deoxyguanosine adduct (OTB-dG). Although research on other adducts stresses the importance ...
  • Graham, J. B.; Cordes, A. W.; Oakley, Richard T.; Boeré, René T. (International Union of CrystallographyUniversity of ArkansasUniversity of Guelph, 1985)
    C7HsC12N3S2, Mr=266.17, triclinic, P], a=6-028(1), b=9-985(2), c=10.157 (3) /~, ct= 117.33 (2), fl= 106.73(2), y=90.31(1) °, V= 513-3(4)/~3, Z=2, D x=1.72gcm -3, 2(MoK~t)= 0.71073 A, /1 = 9.85 cm -1, F(000) = 268, T= ...
  • Cordes, A. Wallace; Oakley, Richard T.; Boeré, René T. (International Union of CrystallographyUniversity of ArkansasUniversity of Guelph, 1985)
    7-Phenyl- 124324b'2,524-trithia-2,4,6,8,9-penta - azabicyclo[3.3.1]nonane, CTHsNsS 3, M r = 255.3, monoclinic, P2Jn, a = 5.958 (1), b = 22.954 (2), c= 7.428 (1) A,/I= 106.25 (1) °, V= 975.2 (4) A 3, Z=4, D x = 1.74 g ...
  • Boeré, René T.; Ferguson, George; Oakley, Richard T. (International Union of CrystallographyDepartment of Chemistry and BiochemistryUniversity of Guelph, 1986)
    7-Phenyl-3-(triphenylphosphinimino)- 1,3,5,- 2,4,6,8-trithiatetrazocine, C25H20N5PS3, Mr = 517.64, monoclinic, P21/c, a = 13.957 (3), b = 9.242 (3), c = 19.473 (4)/k, fl= 102.80 (2) °, V= 2449.4 A 3, Z =4, Dx=l.4Ogcm ...
  • Boeré, René T.; Oakley, Richard T.; Cordes, A. Wallace (International Union of CrystallographyUniversity of GuelphUniversity of Arkansas, 1985)
    7-tert-Butyl-3-chloro- 1,3,5,2,4,6,8-trithiatetrazocine, CsH9C1N4S 3, Mr= 256"8, tetragonal, P42/n, a = 17.856 (2), c = 6.646 (1) A, V = 2118.9 (8)/k 3, z=8, Dx= 1.61gcm -3, 2(MoKa)=0.71073A, # =8.9cm -1, F(000)=1056, ...
  • Cordes, A. Wallace; Craig, S. L.; Privett, J. A. James; Oakley, Richard T.; Boeré, René T. (International Union of CrystallographyUniversity of ArkansasUniversity of Guelph, 1986)
    10-Phenyl- 1,8-dithia-9,11,12-triazatetracyclo- [6.3.1.1 a,6.02,7]tfideca- 1 (11),4,9,8 (12)-tetraene, C ~4- H13N3S2, Mr-- 287.4, monoclinic, P2 l, a = 5-789 (2), b=10.064(1), c--11.109(2)A, fl=94.78(2) °, V = 644.9 ...
  • Boeré, René T.; Zhang, Yuankui (International Union of CrystallographyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2013)
    The title compound, C45H70P+ ClO4 or [Tripp3PH+][ClO4 ], was produced from the perchlorate salt of the corresponding radical cation Tripp3P + through very slow H-atom abstraction reactions in a solution of ...
  • Closson, Taunia L. L.; Roussel, Marc R. (American Physical SocietyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridgehttps://doi.org/10.1103/PhysRevLett.85.3974, 2000)
    Many natural and technological systems have on/off switches. For instance, mitosis can be halted by biochemical switches which act through the phosphorylation state of a complex called mitosis promoting factor. If switching ...
  • El Bourakadi, Khadija; El Mehdi Mekhzoum, Mohamed; Boeré, René T.; El Kacem Qais, Abou; Bouhfid, Rachid (ElsevierArts and ScienceDepartment of Chemistry and BiochemistryInstitute of Nanomaterial and Nanotechnology (NANOTECH)Mohammed V-Rabat UniversityUniversity of Lethbridgehttps://doi.org/10.1016/j.molstruc.2019.127253, 2019)
    6-bis(2-(thiazol-4-yl)-benzimidazol-1-yl)hexane has been efficiently synthesized by direct alkylation of 2-(4-thiazolyl)benzimidazole with 1,6-dibromohexane via phase-transfer catalysis. The desired compound was obtained ...