Browsing Faculty Research and Publications by Title

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  • Heineken, Tsuchiya and Aris on the mathematical status of the pseudo-steady state hypothesis: a classic from volume 1 of Mathematical Biosciences 
    Roussel, Marc R. (ElsevierArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridgehttps://doi.org/10.1016/j.mbs.2019.108274, 2019)
    Volume 1, Issue 1 of Mathematical Biosciences was the venue for a now-classic paper on the application of singular perturbation theory in enzyme kinetics, “On the mathematical status of the pseudo-steady state hypothesis ...
  • High Z’ structures of 1,2,3,5-dithiadiazolyls and of 1,2,3,5-diselenadiazolyls containing the first structurally characterized monomeric diselenadiazolyls 
    Boeré, René T.; Hill, Nathan D. D. (Royal Society of ChemistryArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridgehttps://doi.org/10.1039/C7CE00863E, 2017)
    Crystals of 4-[3-(trifluoromethyl)phenyl]-3H-1,2,3,5-dithiadiazol-3-yl grown by slow sublimation in a three-zone furnace form in P1 ̅ with Z = 12. The six independent molecules combine into two cis-oid and one twisted ...
  • Hydrogen-bonded networks in oxygen-coordinated monoamide complexes of zinc(II) 
    Amrei, Leila M.; Boeré, René T. (NRC Research PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridgehttps://www.nrcresearchpress.com/journal/cjc, 2018)
    The preparation of the bulky secondary amideN-(2,6-diisopropylphenyl)-2,2-dimethylpropanamide and the determi-nation of its crystal structure at 173(2) K are reported. The structure displays disorder of thetBu methyl groups ...
  • Hydrogen-bonding interactions in T-2 toxin studies using solution and solid-state NMR 
    Chaudhary, Praveen; Shank, Roxanne A.; Montina, Tony; Goettel, James T.; Foroud, Nora A.; Hazendonk, Paul; Eudes, François (M D P I A GArts and ScienceDepartment of Chemistry & BiochemistryUniversity of LethbridgeAgriculture and Agri-Food Canada, 2011)
    The structure of T-2 toxin in the solid-state is limited to X-ray crystallographic studies, which lack sufficient resolution to provide direct evidence for hydrogen-bonding interactions. Furthermore, its solution-structure, ...
  • Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition 
    Dzananovic, Edis; Astha; Chojnowski, Grzegorz; Deo, Soumya; Booy, Evan P.; Padilla-Meier, Pauline; McEleney, Kevin; Bujnicki, Janusz M.; Patel, Trushar R.; McKenna, Sean A. (Public Library of Science, 2017)
    Highly structured RNA derived from viral genomes is a key cellular indicator of viral infection. In response, cells produce the interferon inducible RNA-dependent protein kinase (PKR) that, when bound to viral dsRNA, ...
  • Infrared diode laser spectroscopy of the CCO radical: the 2v1-v1 and v1+v3-v3 difference bands 
    Moazzen-Ahmadi, N.; Boeré, René T. (AIP PublishingArts and ScienceDepartment of ChemistryDepartment of PhysicsUniversity of Lethbridgehttps://doi.org/10.1063/1.476073, 1998)
    The 2n 12n 1 and n 11n 32n 3 difference bands of the CCO radical in the gas phase have been studied using a tunable infrared diode laser spectrometer. The CCO radical was produced using a flowing mixture of carbon suboxide ...
  • Inorganic and organometallic radicals of main group elements 
    Boeré, René T. (Royal Society of ChemistryArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2013)
    [No abstract available]
  • A mathematical model of the biochemical network underlying left-right asymmetry establishment in mammals 
    Roussel, Catharine J.; Roussel, Marc R. (ElsevierArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge10.1016/j.biosystems.2018.10.003, 2018)
    The expression of the TGF-β protein Nodal on the left side of vertebrate embryos is a determining event in the development of internal-organ asymmetry. We present a mathematical model for the control of the expression of ...
  • Metal carbonyl complexes of phosphaamidines: coordinative integrity detected in C-amino(λ3,σ2)phosphaalkene isomers coordinated through n(P) HOMO−1 donor orbitals 
    Masuda, Jason D.; Boeré, René T. (Royal Society of ChemistryArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2016)
    Metal(0) complexes L(Cr,Mo,W)(CO)5 have been prepared from 1,3-bis(2,6-diisopropylphenyl)-2(4-methylphenyl)-3-aza-1(λ3,σ2)-phosphapropene and 1,3-bis(2,6-diisopropylphenyl)-2-(4-methoxyphenyl)-3-aza-1(λ3,σ2)-phosphapropene ...
  • Mono- and bis-imidazolidinium ethynyl cations and the reduction of the latter to give an extended bis-1,4-([3]cumulene)-p-carbo-quinoid system 
    Barry, Brian M.; Soper, R. Graeme; Hurmalainen, Juha; Mansikkamäki, Akseli; Robertson, Katherine N.; McClennan, William L.; Veinot, Alex J.; Roemmele, Tracey L.; Werner-Zwanziger, Ulrike; Boeré, René T.; Tuononen, Heikki M.; Clyburne, Jason A. C.; Masuda, Jason D. (WileyArts and ScienceDepartment of Chemistry and BiochemistrySaint Mary's UniversityUniversity of Wisconsin-PlattevilleUniversity of JyvaskylaUniversity of LethbridgeDalhousie Universityhttps://doi.org/10.1002/anie.201711031, 2017)
    An extended π-system containing two [3]cumulene fragments separated by a p-carbo-quinoid and stabilized by two capping N-heterocyclic carbenes (NHCs) has been prepared. Mono- and bis-imidazolidinium ethynyl cations have ...
  • Multioscillatory state in a yeast continuous culture studies by membrane-inlet mass spectrometry 
    Roussel, Marc R.; Lloyd, David (Arts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2007)
  • De novo cytosine methylation in the differentiating macronucleus of the stichotrichous ciliate Stylonychia lemnae 
    Juranek, Stefan; Wieden, Hans-Joachim; Lipps, Hans J. (Oxford University PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Witten/HerdeckeUniversity of Lethbridgehttps://doi.org/10.1093/nar/gkg233, 2003)
    Dramatic DNA reorganization and elimination processes occur during macronuclear differentiation in ciliates. In this study we analyzed whether cytosine methylation of specific sequences plays a functional role during DNA ...
  • On the distribution of transcription times 
    Roussel, Marc R. (Biomath ForumArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2013)
    A previously studied model of prokaryotic transcription [Roussel and Zhu, Bull. Math. Biol. 68 (2006) 1681--1713] is revisited. The first four moments of the distribution of transcription times are obtained analytically ...
  • Pre-steady-state kinetic analysis of the three Escherichia coli pseudouridine synthases TruB, TruA, and RluA reveals uniformly slow catalysis 
    Wright, Jaden R.; Keffer-Wilkes, Laura C.; Dobing, Selina R.; Wieden-Kothe, Ute (Cold Springs Harbor Laboratory PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2011)
    Pseudouridine synthases catalyze formation of the most abundant modification of functional RNAs by site-specifically isomerizing uridines to pseudouridines. While the structure and substrate specificity of these enzymes ...
  • Preparation and x-ray structure of 4-N,N'-bis(trimethylsilyl)- amino-3,5-diisopropylphenylselenium trichloride 
    Maaninen, Arto; Boeré, René T.; Chivers, Tristram; Parvez, Masood (Verlag der Zeitschrift für NaturforschungArts and ScienceDepartment of Chemistry and BiochemistryUniversity of OuluUniversity of LethbridgeUniversity of Calgary, 1999)
    The reaction of SeCU or SeCF with /V,/V’-bis(trimethylsilyl)-2,6-diisopropylaniline occurs not at the nitrogen atom but by electrophilic aromatic substitution at C-4 of the phenyl ring to give [(CH3)3Si]2NC6H2('Pr:)SeCl3, ...
  • Reproducibility of fluorescent expression from engineering biological constructs in E. coli 
    Beal, Jacob; Haddock-Angelli, Traci; Gershater, Markus; De Mora, Kim; Lizarazo, Meagan; Hollenhorst, Jim; Rettberg, Randy; iGEM Interlab Study Contributors (Public Library of ScienceArts and ScienceDepartment of Chemistry and BiochemistryRaytheon BBN TechnologiesiGEM FoundationSynthaceAgilentUniversity of Lethbridge, 2016)
    We present results of the first large-scale interlaboratory study carried out in synthetic biology, as part of the 2014 and 2015 International Genetically Engineered Machine (iGEM) competitions. Participants at 88 institutions ...
  • Ruthenium(II)-arene complexes with monodentate aminopyridine ligands: insights into redox stability, electronic structures and biological activity 
    Marszaukowskia, Flávia; Guimarãesa, Ivelise Dimbarre Lao; da Silvaa, Juliana Paula; da Silveira Lacerda, Luis Henrique; de Lazaroa, Sergio Ricardo; de Araujob, Márcio Peres; Castellena, Patrícia; Tominaga, Tania Toyomi; Boeré, René T.; Wohnrath, Karen (ElsevierArts and ScienceDepartment of Chemistry and BiochemistryUniversidade Estadual de Ponta GrossaUniversidade Federal do ParanáUniversidade Estadual do Centro-OesteUniversity of Lethbridge, 2019)
    The synthesis and spectroscopic characterization of four ruthenium(II) arene complexes with monodentate pyridine derivatives ([( 6–p-cymene)RuCl2L]: L = 2-aminopyridine, 2-methylaminopyridine, 2-benzylaminopyridine, and ...
  • The scale-free dynamics of eukaryotic cells 
    Aon, Miguel A.; Roussel, Marc R.; Cortassa, Sonia; O'Rourke, Brian; Murray, Douglas B.; Beckmann, Manfred; Lloyd, David (Public Library of ScienceArts and ScienceDepartment of Chemistry and BiochemistryJohns Hopkins University Institute of Molecular CardiobiologyUniversity of LethbridgeKeio UniversityUniversity of WalesCardiff University, 2008)
    Temporal organization of biological processes requires massively parallel processing on a synchronized time-base. We analyzed time-series data obtained from the bioenergetic oscillatory outputs of Saccharomyces cerevisiae ...
  • Short contacts of the sulphur atoms of a 1,2,3,5-dithiadiazolyl dimer with triphenylstibine: first cocrystal with an aromatic compound 
    Boeré, René T. (Royal Society of ChemistryArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Lethbridge, 2016)
    The structure of dimeric 2,7-bisij4-(trifluoromethyl)phenyl]-4λ4,5λ4,9λ4,10λ4-tetrathietoij1,2-a:3,4-a′]bis [1,2,3,5]dithiadiazole (C8H4F3N2S2)2 and its adduct with triphenylstibin (C8H4F3N2S2)2·C18H15Sb, both have triclinic ...
  • The signal recognition particle binds to protein L23 at the peptide exit of the Escherichia coli ribosome 
    Gu, Shan-Qing; Peske, Frank; Wieden, Hans-Joachim; Rodnina, Marina V.; Wintermeyer, Wolfgang (Cold Springs Harbor Laboratory PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of Witten/HerdeckeUniversity of Lethbridge, 2003)
    The signal recognition particle (SRP) from Escherichia coli, composed of Ffh protein and 4.5S RNA, mediates membrane targeting of translating ribosomes displaying a signal or signal-anchor sequence. SRP binds at the peptide ...