University of Lethbridge Research Repository: Recent submissions

  • Marasco, Rafaela de Castro; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : Universtiy of Lethbridge, Department of GeographyArts and ScienceDepartment of Geography, 2018)
    Income inequality and income polarization have risen sharply in many Canadian Metropolitan Areas, especially in the Calgary CMA which is Canada’s second most unequal city. Housing affordability is a concern for a growing ...
  • Wang, Chaowen; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : Universtiy of Lethbridge, Department of GeographyArts and ScienceDepartment of Geography, 2018)
    Social media has revolutionized many aspects of people’s social life. However, few studies have utilized massive individual-level data from social media to examine the effects of geography. In this study a program was ...
  • Badenhorst, Cecilia; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : Universtiy of Lethbridge, Department of NeuroscienceArts and ScienceDepartment of Neuroscience, 2018)
    Stress is the response to a perceived or real threat. Acute incidences of stress can be beneficial. However, repeated stress can cause maladaptive changes in brain and behavior leading to neuropsychiatric illnesses. Among ...
  • Toscano de Araujo, Gabriela; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : Universtiy of Lethbridge, Department of Biological SciencesArts and ScienceDepartment of Biological Sciences, 2018)
    Wheat (Triticum aestivum L.) is affected by widespread fungal diseases that can severely decrease yield and grain quality. Threshold concentrations of stripe rust and powdery mildew spores required for disease development ...
  • Howard, Lisa (Sciedu Press, 2018)
    Background and objective: Motivational interviewing (MI) is a communication style adopted by health professionals to support patient-centered decision making about behavior change. Little is known about how patients respond ...
  • Muhumed, Hassan Abdullahi; University of Lethbridge. Dhillon School of Business (Lethbridge, Alta. : University of Lethbridge, Dhillon School of BusinessDhillon School of Business, 2018-08-23)
    There is overwhelming agreement among scholars and practitioners alike on the socio-economic importance of Small-and Medium-sized Enterprises (SMEs), both in developed and developing countries. However, there is also ...
  • Kewley, Erika; McBride, Dawn Lorraine (The Ontario Shores Centre for Mental Health Sciences and McMaster UniversityEducationUniversity of Lethbridge, 2013)
    This manuscript presents a critical analysis of the ethical implications when mental health professionals, such as psychologists, use data from their clients’ assessments for research purposes. The ethical premise, drawn ...
  • Schuilenberg, Susannah-Joy; Warren, Meg; Crookes, Annie; Al Serkal, Alia; Donaldson, Scott I.; McBride, Dawn Lorraine (Middle East Journal of Positive PsychologyEducationWilliam & Associates Consultant ServicesInternational Positive Psychology AssociationWestern Positive Psychology Association (USA)Heriot-watt Universitydu Telecommunications (UAE)Claremont Graduate UniversityUniversity of Lethbridge, 2016)
    Professional associations have a mandate to protect and regulate those members deemed qualified to provide mental health services to the public. This is accomplished through supervision and policing of practitioners’ ...
  • Marco, Amy S.; McBride, Dawn Lorraine; Johanson, Gregory (Hakomi InstituteEducationUniversity of Lethbridge, 2012)
    This article introduces readers to Hakomi in an alternative manner. Rather than present an overview of the interventions associated with the principles, it provides a personal narrative illustrating how the principles are ...
  • Kovalchuk, Anna; Ilnytskyy, Yaroslav; Rodriquez-Juarez, Rocio; Katz, Amanda; Sidransky, David; Kolb, Bryan; Kovalchuk, Olga (Impact JournalsArts and ScienceDepartment of Biological SciencesDepartment of NeuroscienceUniversity of LethbridgeChampions OncologyUniversity of Calgary, 2017)
    A wide array of central nervous system complications, neurological deficits, and cognitive impairments occur and persist as a result of systemic cancer and cancer treatments. This condition is known as chemo brain and it ...
  • Wang, Bo; Li, Dongping; Sidler, Corinne; Rodriquez-Juarez, Rocio; Singh, Natasha; Heyns, Mieke; Ilnytskyy, Yaroslav; Bronson, Roderick T.; Kovalchuk, Olga (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of LethbridgeQiqihar Medical UniversityThe Dana Farber/Harvard Comprehensive Cancer Center, 2015)
    Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related deaths worldwide, and it has been linked to radiation exposure. As a well-defined oncogene, wild-type p53-induced phosphatase 1 (WIP1) plays ...
  • Kochan, David Z.; Kovalchuk, Olga (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of Lethbridge, 2015)
    Breast cancer is already the most common malignancy affecting women worldwide, and evidence is mounting that breast cancer induced by circadian disruption (CD) is a warranted concern. Numerous studies have investigated ...
  • Luzhna, Lidiya; Lykkesfeldt, Anne E.; Kovalchuk, Olga (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of LethbridgeDanish Cancer Society Research Center, 2015)
    Endocrine therapy agents (the selective estrogen receptor (ER) modulators such as tamoxifen or the selective ER down-regulators such as ICI 182,780) are key treatment regimens for hormone receptor-positive breast cancers. ...
  • Kovalchuk, Anna; Mychasiuk, Richelle; Muhammad, Arif; Hossain, Shakhawat; Ilnytskyy, Slava; Ghose, Abhijit; Kirby, Charles; Ghasroddashti3, Esmaeel; Kovalchuk, Olga; Kolb, Bryan (Impact JournalsArts and ScienceDepartment of Biological SciencesDepartment of NeuroscienceUniversity of LethbridgeAlberta Health ServicesUniversity of CalgaryAlberta Epigenetics NetworkCanadian Institute for Advanced Research, 2016)
    Radiation therapy can not only produce effects on targeted organs, but can also influence shielded bystander organs, such as the brain in targeted liver irradiation. The brain is sensitive to radiation exposure, and ...
  • Krishnan, Preethi; Ghosh, Sunita; Graham, Kathryn; Mackey, John R.; Kovalchuk, Olga; Damaraju, Sambasivarao (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of AlbertaAlberta Health ServicesUniversity of Lethbridge, 2016)
    Piwi-interacting RNAs (piRNAs), whose role in germline maintenance has been established, are now also being classified as post-transcriptional regulators of gene expression in somatic cells. PIWI proteins, central to piRNA ...
  • Lezhnina, Ksenia; Kovalchuk, Olga; Zhavoronkov, Alexander A.; Korzinkin, Mikhail B.; Zabolotneva, Anastasia A.; Shegay, Peter V.; Sokov, Dmitry G.; Gaifullin, Nurshat M.; Rusakov, Igor G.; Aliper, Alexander M.; Roumiantsev, Sergey A.; Alekseev, Boris Y.; Borisov, Nikolay M.; Buzdin, Anton A. (Impact JournalsArts and ScienceDepartment of Biological SciencesPathway PharmaceuticalsD. Rogachyov Federal Research Center of Pediatric Hematology, Oncology and ImmunologyUniversity of LethbridgeCanada Cancer and Aging Research Laboratories Ltd.John Hopkins UniversityMoscow Institute of Physics and TechnologyShemyakn-Ovchinnikov Institute of Bioorganic ChemistryP.A. Herzen Moscow Oncological Research InstituteMoscow 1st Oncological HospitalLomonosov Moscow State UniversityRussian Medical Postgraduate AcademyA.I. Burnasyan Federal Medical Biophysical Center, 2014)
    We recently proposed a new bioinformatic algorithm called OncoFinder for quantifying the activation of intracellular signaling pathways. It was proved advantageous for minimizing errors of high-throughput gene expression ...
  • Singhal, Sandeep K.; Usmani, Nawaid; Michiels, Stefan; Metzger-Filho, Otto; Saini, Kamal S.; Kovalchuk, Olga; Parliament, Matthew (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of AlbertaService de Biostatistique et d'EpidemiologieUniversité Paris-SudHarvard Medical SchoolQuantum Health Analytics SPRLUniversity of LethbridgeCanada Cancer and Aging Research Laboratories Ltd., 2016)
    Until recently, an elevated disease risk has been ascribed to a genetic predisposition, however, exciting progress over the past years has discovered alternate elements of inheritance that involve epigenetic regulation. ...
  • Wang, Justin; Wu, Chiping; Peng, Jessie; Patel, Nisarg; Huang, Yayi; Gao, Xiaoxing; Aljarallah, Salman; Eubanks, James H.; McDonald, Robert; Zhang, Liang (Public Library of ScienceArts and ScienceDepartment of NeuroscienceToronto Western Research InstituteUniversity of TorontoUniversity of LethbridgeKing Saud University, 2015)
    Aging is associated with an increased risk of seizures/epilepsy. Stroke(ischemic or hemorrhagic) and cardiac arrest related brain injury are two major causative factors for seizure development in this patient population. ...
  • Aimaiti, Nuerrennisahan (Nurgul); University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : Universtiy of Lethbridge, Department of Mathematics and Computer ScienceArts and ScienceDepartment of Mathematics and Computer Science, 2018)
    Matrix computation is an important area in high-performance scientific computing. Major computer manufacturers and vendors typically provide architecture- aware implementation libraries such as Basic Linear Algebra Subroutines ...
  • Mirza Agha, Behroo; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : Universtiy of Lethbridge, Department of NeuroscienceArts and ScienceDepartment of Neuroscience, 2018)
    The current thesis investigated the role of acetylcholine in recovery from diaschisis and skilled hand movement following ischemic stroke in a mouse model of photothrombotic stroke. Mice were trained in skilled reaching ...