Biological Sciences: Recent submissions

  • Schwalm, Christopher R.; Williams, Christopher A.; Schaefer, Kevin; Anderson, Ryan S.; Arain, M. Altaf; Baker, Ian T.; Barr, Alan G.; Black, T. Andrew; Chen, Guangsheng; Chen, Jing M.; Ciais, Philippe; Davis, Kenneth J.; Desai, Ankur R.; Dietze, Michael C.; Dragoni, Danilo; Fischer, Marc L.; Flanagan, Larry B.; Grant, Robert F.; Gu, Lianhong; Hollinger, David Y.; Izaurralde, R. Cesar; Kucharik, Christopher J.; Lafleur, Peter M.; Law, Beverly E.; Li, Longhui; Li, Zhengpeng; Liu, Shuguang; Lokupitiya, Erandathie; Luo, Yiqi; Ma, Siyan; Margolis, Hank; Matamala, Roser; McCaughey, Harry; Monson, Russell K.; Oechel, Walter C.; Peng, Changhui; Poulter, Benjamin; Price, David T.; Ricciuto, Daniel M.; Riley, William J.; Sahoo, Alok Kumar; Sprintsin, Michael; Sun, Jianfeng; Tian, Hanqin; Tonitto, Christina; Verbeeck, Hans; Verma, Shashi B. (American Geophysical UnionArts and ScienceDepartment of Biological SciencesClark UniversityUniversity of Colorado at BoulderUniversity of MontanaMcMaster UniversityColorado State UniversityAtmospheric Science and Technology DirectorateUniversity of British ColumbiaAuburn UniversityUniversity of TorontoLaboratoire des Sciences du Climat et de l'EnvironmentPennsylvania State UniversityUniversity of Wisconsin-MadisonUniversity of Illinoise at Urbana-ChampaignIndiana UniversityLawrence Berkeley National LaboratoryUniversity of LethbridgeUniversity of AlbertaOak Ridge National LaboratoryUSDA Forest ServicePacific Northwest National LaboratoryUniversity of MarylandTrent UniversityOregon State UniversityASRC Research and Technology SolutionsEarth Resources Observation and Science CenterUniversity of OklahomaUniversity of CaliforniaUniversite LavalArgonne National LaboratoryQueen's UniversitySan Diego State UniversityUniversity of Quebec at MontrealSwiss Federal Research InstituteCanadian Forest ServicePrinceton UniversityCornell UniversityGhent UniversityUniversity of Nebraska-Lincoln, 2010)
    Our current understanding of terrestrial carbon processes is represented in various models used to integrate and scale measurements of CO2 exchange from remote sensing and other spatiotemporal data. Yet assessments are ...
  • Dietze, Michael C.; Vargas, Rodrigo; Richardson, Andrew D.; Stoy, Paul C.; Barr, Alan G.; Anderson, Ryan S.; Arain, M. Altaf; Baker, Ian T.; Black, T. Andrew; Chen, Jing M.; Philippe, Ciais; Flanagan, Larry B.; Gough, Christopher M.; Grant, Robert F.; Hollinger, David Y.; Izaurralde, R. Cesar; Kucharik, Christopher J.; Lafleur, Peter M.; Liu, Shugang; Lokupitiya, Erandathie; Luo, Yiqi; Munger, J. William; Peng, Changhui; Poulter, Benjamin; Price, David T.; Ricciuto, Daniel M.; Riley, William J.; Sahoo, Alok Kumar; Schaefer, Kevin; Suyker, Andrew E.; Tian, Hanqin; Tonitto, Christina; Verbeeck, Hans; Verma, Shashi B.; Wang, Weifeng; Weng, Ensheng (American Geophysical UnionArts and ScienceDepartment of Biological SciencesUniversity of Illinoise at Urbana-ChampaignCentro de Investigacion Cientifica y de Educacion Superior de EnsenadaHarvard UniversityMontana State UniversityAtmospheric Science and Technology DirectorateUniversity of MontanaMcMaster UniversityColorado State UniversityUniversity of British ColumbiaUniversity of TorontoCentre d'Etudes Orme des MerisiersUniversity of LethbridgeVirginia Commonwealth UniversityUniversity of AlbertaU.S. Department of Agriculture Forest ServicePacific Northwest National LaboratoryUniversity of MarylandUniversity of Wisconsin-MadisonTrent UniversityEarth Resources Observation and Science CenterUniversity of OklahomaUniversity of Quebec at MontrealSwiss Federal Research InstituteLaboratoire des Sciences du Climat et de l'EnvironmentCanadian Forest ServiceOak Ridge National LaboratoryLawrence Berkeley National LaboratoryPrinceton UniversityUniversity of Colorado at BoulderUniversity of Nebraska-LincolnAuburn UniversityCornell UniversityGhent University, 2011)
    Ecosystem models are important tools for diagnosing the carbon cycle and projecting its behavior across space and time. Despite the fact that ecosystems respond to drivers at multiple time scales, most assessments of model ...
  • Sims, Daniel A.; Rahman, Abdullah F.; Cordova, Vicente D.; El-Masri, Bassil Z.; Baldocchi, Dennis D.; Flanagan, Larry B.; Goldstein, Allen H.; Hollinger, David Y.; Misson, Laurent; Monson, Russell K.; Oechel, Walter C.; Schmid, Hans P.; Wofsy, Steven C.; Xu, Liukang (American Geophysical UnionArts and ScienceDepartment of Biological SciencesBall State UniversityTexas Tech UniversityUniversity of CaliforniaUniversity of LethbridgeNortheastern Research StationUniversity of Colorado at BoulderSan Diego State UniversityIndiana UniversityHavard UniversityLicor Incorporated Environmental, 2006)
    Carbon flux models based on light use efficiency (LUE), such as the MOD17 algorithm, have proved difficult to parameterize because of uncertainties in the LUE term, which is usually estimated from meteorological variables ...
  • Sulman, Benjamin N.; Desai, Ankur R.; Schroeder, Nicole M.; Ricciuto, Daniel M.; Barr, Alan G.; Richardson, Andrew D.; Flanagan, Larry B.; Lafleur, Peter M.; Tian, Hanqin; Chen, Guangsheng; Grant, Robert F.; Poulter, Benjamin; Verbeeck, Hans; Ciais, Philippe; Ringeval, Bruno; Baker, Ian T.; Schaefer, Kevin; Luo, Yiqi; Wong, Ensheng (American Geophysical UnionArts and ScienceDepartment of Biological SciencesUniversity of Wisconsin-MadisonOak Ridge National LaboratoryEnvironment CanadaHarvard UniversityUniversity of LethbridgeTrent UniversityAuburn UniversityUniversity of AlbertaSwiss Federal Research InstituteLaboratoire des Sciences du Climat et de l'EnvironmentGhent UniversityColorado State UniversityUniversity of Colorado at BoulderUniversity of Oklahoma, 2012)
    Northern peatlands are likely to be important in future carbon cycle-climate feedbacks due to their large carbon pools and vulnerability to hydrological change. Use of non-peatland-specific models could lead to bias in ...
  • Humphreys, Elyn R.; Lafleur, Peter M.; Flanagan, Larry B.; Hedstrom, Newell; Syed, Kamran H.; Glenn, Aaron J.; Granger, Raoul (American Geophysical UnionArts and ScienceDepartment of Biological SciencesTrent UniversityUniversity of LethbridgeNational Hydrology Research Centre, 2006)
    Northern peatlands are a diverse group of ecosystems varying along a continuum of hydrological, chemical, and vegetation gradients. These ecosystems contain about one third of the global soil carbon pool, but it is uncertain ...
  • Grant, Robert F.; Flanagan, Larry B. (American Geophysical UnionArts and ScienceDepartment of Biological SciencesUniversity of AlbertaUniversity of Lethbridge, 2007)
    The confidence with which we can model water deficit effects on grassland productivity is limited by uncertainty about the mechanisms, stomatal and nonstomatal, by which soil water deficits reduce CO2 uptake. We propose ...
  • Adkinson, Angela C.; Syed, Kamran H.; Flanagan, Larry B. (American Geophysical UnionArts and ScienceDepartment of Biological SciencesUniversity of Lethbridge, 2011)
    The large belowground carbon stocks in northern peatland ecosystems are potentially susceptible to release because of the expected differential responses of photosynthesis and respiration to climate change. This study ...
  • Zaheer, Rahat; Bony-Dugat, Eric; Holman, Devon; Cousteix, Elodie; Xu, Yong; Munns, Krysty D.; Selinger, Lorna J.; Barbieri, Rutn; Alexander, Trevor W.; McAllister, Tim A.; Selinger, L. Brent (Public Library of ScienceArts and ScienceDepartment of Biological SciencesLethbridge Research and Development CentreUniversité Paris-SaclayUniversity of Lethbridge, 2017)
    Escherichia coli O157:H7 is a foodborne pathogen that colonizes ruminants. Cattle are considered the primary reservoir of E. coli O157:H7 with super-shedders, defined as individuals excreting>104 E. coli O157:H7 CFU g-1 ...
  • Laing, Chad R.; Buchanan, Cody J.; Taboada, Eduardo N.; Zhang, Yongxiang; Kropinski, Andrew; Villegas, Andre; Thomas, James E.; Gannon, Victor P. J. (BioMed CentralArts and ScienceDepartment of Biological SciencesPublic Health Agency of CanadaUniversity of Lethbridge, 2010)
    Background: The pan-genome of a bacterial species consists of a core and an accessory gene pool. The accessory genome is thought to be an important source of genetic variability in bacterial populations and is gained through ...
  • Reti, Kristen L.; Thomas, Matthew C.; Yanke, L. Jay; Selinger, L. Brent; Inglis, G. Douglas (BioMed CentralArts and ScienceDepartment of Biological SciencesAgriculture and Agri-Food Canada Research CentreUniversity of Lethbridge, 2013)
    Background: Antimicrobial growth promoters (AGPs) are antimicrobial agents administered to livestock in feed for prolonged periods to enhance feed efficiency. Beef cattle are primarily finished in confined feeding operations ...
  • Dohms, Kimberly M.; Graham, Brendan A.; Burg, Theresa M. (WileyArts and ScienceDepartment of Biological SciencesUniversity of LethbridgeUniversity of Windsor, 2017)
    An increasing body of studies of widely distributed, high latitude species shows a variety of refugial locations and population genetic patterns. We examined the effects of glaciations and dispersal barriers on the popul ...
  • Macfarlane, Colin B. A.; Natola, Libby; Brown, Mike W. (WileyArts and ScienceDepartment of Biological SciencesUniversity of Lethbridge, 2016)
    Using a combination of mitochondrial and z- linked sequences, microsatellite data, and spatio- geographic modeling, we examined historical and contemporary factors influencing the population genetic structure of the purple ...
  • Kovalchuk, Anna; Ilnytskyy, Yaroslav; Rodriquez-Juarez, Rocio; Katz, Amanda; Sidransky, David; Kolb, Bryan; Kovalchuk, Olga (Impact JournalsArts and ScienceDepartment of Biological SciencesDepartment of NeuroscienceUniversity of LethbridgeChampions OncologyUniversity of Calgary, 2017)
    A wide array of central nervous system complications, neurological deficits, and cognitive impairments occur and persist as a result of systemic cancer and cancer treatments. This condition is known as chemo brain and it ...
  • Wang, Bo; Li, Dongping; Sidler, Corinne; Rodriquez-Juarez, Rocio; Singh, Natasha; Heyns, Mieke; Ilnytskyy, Yaroslav; Bronson, Roderick T.; Kovalchuk, Olga (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of LethbridgeQiqihar Medical UniversityThe Dana Farber/Harvard Comprehensive Cancer Center, 2015)
    Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related deaths worldwide, and it has been linked to radiation exposure. As a well-defined oncogene, wild-type p53-induced phosphatase 1 (WIP1) plays ...
  • Kochan, David Z.; Kovalchuk, Olga (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of Lethbridge, 2015)
    Breast cancer is already the most common malignancy affecting women worldwide, and evidence is mounting that breast cancer induced by circadian disruption (CD) is a warranted concern. Numerous studies have investigated ...
  • Luzhna, Lidiya; Lykkesfeldt, Anne E.; Kovalchuk, Olga (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of LethbridgeDanish Cancer Society Research Center, 2015)
    Endocrine therapy agents (the selective estrogen receptor (ER) modulators such as tamoxifen or the selective ER down-regulators such as ICI 182,780) are key treatment regimens for hormone receptor-positive breast cancers. ...
  • Kovalchuk, Anna; Mychasiuk, Richelle; Muhammad, Arif; Hossain, Shakhawat; Ilnytskyy, Slava; Ghose, Abhijit; Kirby, Charles; Ghasroddashti3, Esmaeel; Kovalchuk, Olga; Kolb, Bryan (Impact JournalsArts and ScienceDepartment of Biological SciencesDepartment of NeuroscienceUniversity of LethbridgeAlberta Health ServicesUniversity of CalgaryAlberta Epigenetics NetworkCanadian Institute for Advanced Research, 2016)
    Radiation therapy can not only produce effects on targeted organs, but can also influence shielded bystander organs, such as the brain in targeted liver irradiation. The brain is sensitive to radiation exposure, and ...
  • Krishnan, Preethi; Ghosh, Sunita; Graham, Kathryn; Mackey, John R.; Kovalchuk, Olga; Damaraju, Sambasivarao (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of AlbertaAlberta Health ServicesUniversity of Lethbridge, 2016)
    Piwi-interacting RNAs (piRNAs), whose role in germline maintenance has been established, are now also being classified as post-transcriptional regulators of gene expression in somatic cells. PIWI proteins, central to piRNA ...
  • Lezhnina, Ksenia; Kovalchuk, Olga; Zhavoronkov, Alexander A.; Korzinkin, Mikhail B.; Zabolotneva, Anastasia A.; Shegay, Peter V.; Sokov, Dmitry G.; Gaifullin, Nurshat M.; Rusakov, Igor G.; Aliper, Alexander M.; Roumiantsev, Sergey A.; Alekseev, Boris Y.; Borisov, Nikolay M.; Buzdin, Anton A. (Impact JournalsArts and ScienceDepartment of Biological SciencesPathway PharmaceuticalsD. Rogachyov Federal Research Center of Pediatric Hematology, Oncology and ImmunologyUniversity of LethbridgeCanada Cancer and Aging Research Laboratories Ltd.John Hopkins UniversityMoscow Institute of Physics and TechnologyShemyakn-Ovchinnikov Institute of Bioorganic ChemistryP.A. Herzen Moscow Oncological Research InstituteMoscow 1st Oncological HospitalLomonosov Moscow State UniversityRussian Medical Postgraduate AcademyA.I. Burnasyan Federal Medical Biophysical Center, 2014)
    We recently proposed a new bioinformatic algorithm called OncoFinder for quantifying the activation of intracellular signaling pathways. It was proved advantageous for minimizing errors of high-throughput gene expression ...
  • Singhal, Sandeep K.; Usmani, Nawaid; Michiels, Stefan; Metzger-Filho, Otto; Saini, Kamal S.; Kovalchuk, Olga; Parliament, Matthew (Impact JournalsArts and ScienceDepartment of Biological SciencesUniversity of AlbertaService de Biostatistique et d'EpidemiologieUniversité Paris-SudHarvard Medical SchoolQuantum Health Analytics SPRLUniversity of LethbridgeCanada Cancer and Aging Research Laboratories Ltd., 2016)
    Until recently, an elevated disease risk has been ascribed to a genetic predisposition, however, exciting progress over the past years has discovered alternate elements of inheritance that involve epigenetic regulation. ...