Browsing Metz, Gerlinde by Title

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  • Olson, David M.; Severson, Emily M.; Verstraeten, Barbara S. E.; Ng, Jane W. Y.; McCreary, J. Keiko; Metz, Gerlinde A. S. (M D P I A GArts and ScienceDepartment of NeuroscienceUniversity of AlbertaUniversity of Lethbridge, 2015)
    Preterm birth is a universal health problem that is one of the largest unmet medical needs contributing to the global burden of disease. Adding to its complexity is that there are no means to predict who is at risk when ...
  • Yao, Youli; Robinson, Alexandra M.; Zucchi, Fabiola C. R.; Robbins, Jerrah C.; Babenko, Olena M.; Kovalchuk, Olga; Kovalchuk, Igor; Olson, David M.; Metz, Gerlinde A. S. (BioMed CentralArts and ScienceDepartment of Biological SciencesUniversity of LethbridgeUniversity of Alberta, 2014)
    Abstract Background: Chronic stress is considered to be one of many causes of human preterm birth (PTB), but no direct evidence has yet been provided. Here we show in rats that stress across generations has downstream ...
  • Metzler, Megan J.; Saucier, Deborah M.; Metz, Gerlinde A. S. (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeUniversity of Ontario Institute of Technology, 2013)
    Aging is associated with deterioration of skilled manual movement. Specifically, aging corresponds with increased reaction time, greater movement duration, segmentation of movement, increased movement variability, and ...
  • Faraji, Jamshid; Soltanpour, Nabiollah; Ambeskovic, Mirela; Zucchi, Fabiola C. R.; Beaumier, Pierre; Kovalchuk, Igor; Metz, Gerlinde A. S. (Frontiers MediaArts and ScienceDepartment of Biological SciencesDepartment of NeuroscienceUniversity of LethbridgeGolestan University of Medical Sciences (GUMS)Babol University of Medical SciencesUniversity of BrasiliaCanAlt Health Laboratories, 2017)
    In a continuously stressful environment, the effects of recurrent prenatal stress (PS) may accumulate across generations and alter stress vulnerability and resilience. Here, we report in female rats that a family history ...
  • Babenko, Olena M.; Golubov, Andrey; Ilnytskyy, Yaroslav; Kovalchuk, Igor; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of Biological SciencesCanadian Centre for Behavioural NeuroscienceUniversity of LethbridgeUniversity of Calgary, 2012)
    Stress represents a critical influence on motor system function and has been shown to impair movement performance. We hypothesized that stress-induced motor impairments are due to brain-specific changes in miRNA and ...
  • Proft, Juliane; Faraji, Jamshid; Robbins, Jerrah C.; Zucchi, Fabiola C. R.; Zhao, Xiaoxi; Metz, Gerlinde A. S.; Braun, Janice E. A. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of CalgaryUniversity of LethbridgeGolestan University of Medical Sciences, 2011)
    Parkinson’s disease (PD) is a common neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra and the aggregation of a-synuclein into Lewy bodies. Existing therapies address motor ...
  • Erickson, Zachary T.; Falkenberg, Erin A.; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of Lethbridge, 2014)
    The consumption of artificial food dye (AFD) during childhood and adolescence has been linked to behavioural changes, such as hyperactivity. It is possible that the vulnerability to AFDs is modified by prenatal stress. ...
  • Zucchi, Fabiola C. R.; Yao, Youli; Ilnytskyy, Yaroslav; Robbins, Jerrah C.; Soltanpour, Nasrin; Kovalchuk, Igor; Kovalchuk, Olga; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of Biological SciencesDepartment of NeuroscienceUniversity of LethbridgeUniversity of Mato Grosso State, 2014)
    Prenatal stress (PS) represents a critical variable affecting lifetime health trajectories, metabolic and vascular functions. Beneficial experiences may attenuate the effects of PS and its programming of health outcomes ...
  • Gomez-Lopez, Nardhy; Tanaka, Satomi; Zaeem, Zoya; Metz, Gerlinde A. S.; Olson, David M. (Biomed Central LtdArts and ScienceDepartment of NeuroscienceUniversity of AlbertaUniversity of Lethbridge, 2013)
    Background: Parturition has been widely described as an immunological response; however, it is unknown how this is triggered. We hypothesized that an early event in parturition is an increased responsiveness of ...
  • Zucchi, Fabiola C. R.; Yao, Youli; Ward, Isaac D.; Ilnytskyy, Yaroslav; Olson, David M.; Benzies, Karen; Kovalchuk, Igor; Kovalchuk, Olga; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceDepartment of Biological SciencesUniversity of LethbridgeUniversity of Mato Grosso StateUniversity of AlbertaUniversity of Calgary, 2013)
    The gestational state is a period of particular vulnerability to diseases that affect maternal and fetal health. Stress during gestation may represent a powerful influence on maternal mental health and offspring brain ...
  • Faraji, Jamshid; Soltanpour, Nabiollah; Moeeini, Reza; Roudaki, Shabnam; Soltanpour, Nasrin; Abdollahi, Ali-Akbar; Metz, Gerlinde A. S. (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeGolestan University of Medical SciencesBabol University of Medical SciencesAvicenna Institute of Neuroscience, 2014)
    Silent focal ischemic mini infarcts in the brain are thought to cause no clinically overt symptoms. Some populations of hippocampal cells are particularly sensitive to ischemic events, however, rendering hippocampal ...
  • Faraji, Jamshid; Soltanpour, Nabiollah; Moeeini, Reza; Roudaki, Shabnam; Soltanpour, Nasrin; Abdollahi, Ali-Akbar; Metz, Gerlinde A. S. (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeGolestan University of Medical SciencesBabol University of Medical SciencesAvicenna Institute of Neuroscience, 2014)
    Silent focal ischemic mini infarcts in the brain are thought to cause no clinically overt symptoms. Some populations of hippocampal cells are particularly sensitive to ischemic events, however, rendering hippocampal ...
  • Ward, Isaac D.; Zucchi, Fabiola C.R.; Robbins, Jerrah C.; Falkenberg, Erin A.; Olson, David M.; Benzies, Karen; Metz, Gerlinde A. (BioMed CentralArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeUniversity of AlbertaUniversity of Calgary, 2013)
    Peripartum events hold the potential to have dramatic effects in the programming of physiology and behaviour of offspring and possibly subsequent generations. Here we have characterized transgenerational changes in ...