Browsing by Subject "H/ACA sRNP"

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  • Ogailan, Abeer Abdullah; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta : University of Lethbridge, Dept. of Chemistry and BiochemistryArt and ScienceDepartment of Chemistry and Biochemistry, 2017)
    The effect that Dyskeratosis congenita mutations have on ribosome biogenesis has not been fully investigated. Here, I am studying the effect of Dyskeratosis congenita mutations using a yeast model system with the goal of ...
  • Tillault, Anne-Sophie; Fourmann, Jean-Baptiste; Loegler, Christine; Wieden, Hans-Joachim; Wieden-Kothe, Ute; Charpentier, Bruno (Cold Spring Harbor Laboratory PressArts and ScienceDepartment of Chemistry and BiochemistryBipole de l'Université de LorraineUniversity of Lethbridge, 2015)
    In all organisms, several distinct stand-alone pseudouridine synthase (PUS) family enzymes are expressed to isomerizeuridine into pseudouridine (Ψ) by specific recognition of RNAs. In addition, Ψs are generated in Archaea ...